نتایج جستجو برای: ergot
تعداد نتایج: 1627 فیلتر نتایج به سال:
Ergot alkaloids, in their active isomeric form, affect animal health and performance, and adsorbents are used to mitigate toxicities by reducing bioavailability. Adsorbents with high specificity (molecularly imprinted polymers: MIP) adsorb ergot alkaloids in vitro, but require evaluation for biological implications. Using ex vivo myography, synthetic polymers were evaluated for effects on the b...
Research was conducted to determine whether individual ergot alkaloids could induce signs of fescue toxicosis. Nine Angus heifers received single i.v. injections of ergotamine tartrate, ergonovine maleate, and saline vehicle in a simple cross-over design. Each heifer received a different compound each week and all treatments during the study. Physiological traits measured 15 min before and 30, ...
The predominant cool-season forage in the southeastern United States is the tall fescue cultivar Kentucky 31 (KY31). Kentucky 31 possesses an endophyte (), which produces a family of toxins called ergot alkaloids. These toxins negatively affect the physiology of animals on consumption and result in the syndrome known as fescue toxicosis. Currently, the United States annually produces approximat...
Abstract Claviceps purpurea causes ergot, a floral disease of major cereal crops, such as winter rye and triticale. The dark sclerotia formed by C. contain numerous toxic ergot alkaloids, which pose health risk for humans animals when ingested. countermeasures against infection are currently limited to intensive tillage, seed cleaning, crop rotation or integration optical sorting machines remov...
The development of fungal endophytes of the genus Epichloë in grasses results in the production of different groups of alkaloids, whose mechanism and biological spectrum of toxicity can differ considerably. Ergot alkaloids, when present in endophyte-infected tall fescue, are responsible for "fescue toxicosis" in livestock, whereas indole-diterpene alkaloids, when present in endophyte-infected r...
OBJECTIVE The long-term use of levodopa to treat Parkinson's disease (PD) is often limited by the development of motor complications (e.g., levodopa-induced dyskinesia, LID). We hypothesized that a non-ergot dopamine agonist with strong affinity for D3) dopamine receptors (pramipexole) may improve LID in patients taking an ergot D1/D2 dopamine agonist. METHODS Patients with PD and LID being t...
Clinical ergotism as seen today results almost exclusively from the excessive intake of ergotamine tartrate in the treatment of migraine headache. Although both gangrenous and convulsive symptoms are seen in naturally occurring ergotism resulting from the ingestion of fungus infected rye, only gangrenous ergotism has been reported following the excessive ingestion of ergotamine tartrate. The sy...
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