Epithelial cells of human and animal epididymis display features of steroidogenic cells. Rat epididymal epithelial cells in vitro produce androgens which are converted to 17beta-estradiol, and released into the medium. The regulation of the epididymal steroidogenesis is not fully understood but it could be expected that it remains under LH influence. In previous study we observed that the morph...

Monoclonal antibodies (mabs) have been used as a powerful tool for identification of newer sperm proteins. However, conventional hybridoma technology rarely provides chance to obtain mabs to epididymal proteins. To increase this chance, we have used an alternate method of neonatal tolerization. In this protocol, animals were tolerized at birth using testicular proteins followed by immunization ...

The aim of the present study was to investigate the androgen receptor (AR) distribution in epididymal cells of developing rats and the effects of prepubertal epididymal obstruction upon AR distribution in the rat caput epididymis. At 15 days of age, the young rats were divided at random into groups for epididymal ligation or sham operation. In the ligation group the corpus epididymides were lig...

Insulin action on glucose transport and metabolism was studied in paraovarian adipocytes from 3-month-old female rats and compared with insulin action in epididymal adipocytes from closely age-matched males. At maximal insulin concentrations the stimulations of 2-deoxyglucose uptake (4-fold the basal value) and of [U-14C]glucose incorporation into CO2 and total lipids (3- and 2-fold the basal v...

Two cases of epididymal sarcoidosis, presenting as scrotal masses, are described. Biopsies of the epididymis and scalene nodes established the diagnosis. The literature of epididymal sarcoid and its differential diagnosis is discussed.

Sperm samples may be used for assisted reproductive technologies (e.g., farmed or endangered species) or as a source of haploid DNA or sperm-specific RNA. When ejaculated spermatozoa are not available or are very difficult to obtain, as is the case for most wild endangered species, the epididymides of dead animals (e.g., animals that have been found dead, shot by hunters or poachers, or that th...

The proteins of epididymal tissues and fluids recovered from different regions of the mouse epididymis from a natural population and an inbred line were examined by polyacrylamide gel electrophoresis under denaturing conditions. Two epididymal specific peptides on the order of 88 and 20 Kilodaltons (Kd), undetected in serum and testicular extracts, were identified in the initial segment, caput,...

the disposition and cellular organization of the endocrine pancreas were studied in three species of freshwater teleosts viz., labeo bata (hamilton, 1822), sperata aor (hamilton, 1822) and chitala chitala (hamilton, 1822) using histological techniques. in l. bata, the endocrine pancreas tissues were mainly distributed in the adipose tissue among the intestinal coils and adjacent to extrahepatic...

The aim of the present study was to investigate the antidiabetic and renal protective effect of Momordica dioica extract (MDMtE) in streptozotocin-diabetic rats. MDMtE treatment markedly reduced serum glucose, increased serum insulin and urea levels. Study results indicated that the antioxidant enzyme activity of kidney was increased, while thiobarbituric acid reactive substances (TBARS) were r...