The product monographs for some low-molecular-weight heparins (LMWHs) state that anti-factor Xa concentrations should be monitored in the treatment of deep vein thrombosis. This article reviews the pharmacological and epidemiological basis for this recommendation and finds the evidence wanting. Anti-factor Xa activity varies for each LMWH, and evidence from clinical trials using anti-factor Xa ...

The synthesis of existing Persistent Organic Pollutants (POPs) pollution monitoring databases with epidemiological data is considered for identifying some impacts of POPs on human health. This task requires new, rich, data, services and models discovery capabilities from a multitude of monitoring networks and web resources. The FP7 project TaToo (Tagging Tool based on a Semantic Discovery Frame...

Emergency Medical Services (EMS) constitute a unique component of health care at the interface between primary and hospital care. EMS data within the pre-hospital setting represents an unparalleled source of epidemiological and health care information that have so far been neglected for public health monitoring. The European Emergency Data Project (EED Project) thus intends to identify common i...

OBJECTIVES Monitoring of the varicella-zoster virus is becoming an important tool for analysis of the circulation of individual strains of VZV which differ not only at the genomic level, but show a variability in their clinical and epidemiological characteristics. Such data are not available on a large scale from the Czech population and could help understanding the epidemiological and evolutio...

A sentinel network, Obépine , has been designed to monitor SARS-CoV-2 viral load in wastewaters arriving at wastewater treatment plants (WWTPs) France as an indirect macro-epidemiological parameter. The sources of uncertainty such a monitoring system are numerous, and the concentration measurements it provides left-censored contain outliers, which biases results usual smoothing methods. Hence, ...