The aim of this study was to evaluate the effect of age on the hemodynamic responses to intravenous (IV) ephedrine in pediatric patients anesthetized with halothane, nitrous oxide, and oxygen. One hundred ten pediatric patients, ranging in age from 0.1 to 15 yr, were assigned to receive 0.1 mg/kg (n = 55) or 0.2 mg/kg (n = 55) IV ephedrine. General anesthesia was maintained with 1.0 minimum alv...

The separation of ephedrine-type alkaloids and their enantiomers in raw herbs and commercial herbal products was investigated by carrying out enantioselective separation in the first-dimension column (containing beta-cyclodextrin as the chiral selector) of a comprehensive two-dimensional gas chromatography (GC x GC) system, whereas a polar polyethylene glycol capillary column was used for separ...

Bala is important medicinal plant of Ayurvedic system of medicine. Previous works have reported presence of ephedrine in Bala although it has not been reported in other varieties of Bala. Extracts of Sida cordifolia standardized to ephedrine are available in the Indian as well as international market. In western world ephedrine once upon a time was widely used for weight loss but recently it ha...

BACKGROUND The aim of this randomized, double-blind, placebo-controlled study was to evaluate dose effects of ephedrine pretreatment on the onset time and intubating conditions after cisatracurium administration. METHODS A total of 140 adult patients were randomized into 4 groups to receive either 30 µg/kg ephedrine (Group 30, n = 35), 70 µg/kg ephedrine (Group 70, n = 35), 110 µg/kg ephedrin...

BACKGROUND The authors have previously observed an apparent association between rostral spread of spinal anesthesia and choice of intravenous vasopressor given to maintain maternal systolic arterial pressure during cesarean delivery. This study tested the hypothesis that an intravenous infusion of phenylephrine can reduce rostral spread of spinal anesthesia in pregnancy, compared with ephedrine...

AIMS To determine whether the federal regulation of ephedrine and pseudoephedrine, precursors used in illicit methamphetamine production, reduced methamphetamine-related acute care hospital admissions. DESIGN ARIMA-intervention time-series analysis. SETTING California (1983-2000), Arizona and Nevada (1991-2000), USA. MEASUREMENTS Monthly counts of methamphetamine-related acute care hospit...

Using a non-invasive cardiac output monitor (Bo-Med NCCOM 3-R7), we have compared cardiovascular responses, degree of haemodilution and incidence of nausea during extradural Caesarean section in healthy non-labouring mothers given either ephedrine 17.5 mg and 3% Dextran 70 7.5 ml kg-1 before delivery (group A) or volume loading with Dextran 15 ml kg-1 without infusion of ephedrine (group B). Sm...

The Drug Enforcement Administration (DEA) is required, as part of the Methamphetamine Epidemic Elimination Act, to develop annual quotas for the manufacture and importation of ephedrine, pseudoephedrine, and phenylpropanolamine products for legitimate utilization in the U.S. At DEA’s request, IMS Health (IMS) identified an approach for generating estimates of 2005 usage for ephedrine and pseudo...

BACKGROUND The present investigation was designed to provide the first empirical examination of the effects of ephedrine sulfate, an alpha- and beta-adrenergic agonist, on subjective and physiological sexual arousal in women. The purpose was to help elucidate the effects of increased peripheral adrenergic activity on sexual response in women. METHODS Twenty sexually functional women participa...

BACKGROUND Recent studies support the use of alpha-agonists during regional anaesthesia in uncomplicated term pregnancies. We hypothesized that ephedrine and phenylephrine, administered for maternal hypotension following fetal hypoxaemia, are equal in respect of fetal outcome. METHODS At 117-132 days gestation, chronically instrumented, anaesthetized and mechanically ventilated ewes were rand...