Diarrheagenic Escherichia coli (DEC), an important agent of infectious diarrhea, is constantly evolving, making its periodic monitoring necessary. However, the DEC genotypes in Ghana remain uncharacterized. We focused on characterizing molecular serotypes, virulence factors, multilocus sequence types, and phylogenetic relatedness among different pathotypes recovered from stool samples pediatric...

Enterotoxigenic Escherichia coli (ETEC) is one well-established causative agent of diarrhea in the developing countries among young children. This prospective study was performed at Laboratories University Sulaimani (in Sulaymaniyah City/Iraq) from September to October 2021which aimed determine prevalence ETEC children and most colonization factor (CFA/I) ETEC. One hundred twenty-five fresh sto...

Enterotoxigenic Escherichia coli (ETEC) causes childhood diarrhea in developing countries. ETEC strains produce the heat-labile enterotoxin (LT) and/or heat-stable enterotoxins (ST) and encode a diverse set of colonization factors used for adherence to intestinal epithelial cells. We previously found that ETEC secretes a heat-stable protein we designated as ETEC Secreted Factor (ESF) that inhib...

Diarrheagenic Escherichia coli (DEC) are associated with frequent incidences of waterborne infections and pose health risk to individuals who contact water for domestic or recreational uses. Detection DEC pathotypes in drinking can be used as an indicator fecal contamination. This study aimed investigate the occurrence their capacity form biofilms samples collected from different sources. In th...

The expression of the inner membrane protein NlpA is repressed by the enterotoxigenic Escherichia coli (ETEC) virulence regulator Rns, a member of the AraC/XylS family. The Rns homologs CfaD from ETEC and AggR from enteroaggregative E. coli also repress expression of nlpA. In vitro DNase I and potassium permanganate footprinting revealed that Rns binds to a site overlapping the start codon of n...

Abstract Recent studies suggest that the intestinal microenvironment regulate lung immune cells. Conversely, changes in can modulate gut system. Yet, mucosal-associated responses have been studied a compartmentalized manner, as if there is no communication between different organs. Thus, role of gut-lung axis mucosal poorly understood. Using enterotoxigenic Escherichia coli (ETEC), we establish...

background: introduction: enterotoxigenic escherichia coli (etec) is the most important bacterial cause of watery  travelers' diarrhea  in  developing countries. watery diarrhea is can cause serious life-threatening dehydration. etec was caused diarrhea by the secretion of two heat-labile enterotoxins (lts) and the heat-stable enterotoxins (sts) which increase intestinal secretion. routine labo...

We evaluated effect of enterotoxigenic Escherichia coli (ETEC) specific lytic phage CJ12 in ETEC infected pigs. Phage was mixed with feed at a ratio of 1:1,000 (0.1%). One week after initially providing phage mixed feed, pigs were challenged orally with 10(11) CFU of ETEC and body weight, diarrhea score, bacterial CFU and phage PFU in the feces were measured. Pigs of phage treated groups C (10(...

BACKGROUND Enterotoxigenic Escherichia coli (ETEC) is a major diarrheal pathogen in developing countries, where it accounts for millions of infections and hundreds of thousands of deaths annually. While vaccine development to prevent diarrheal illness due to ETEC is feasible, extensive effort is needed to identify conserved antigenic targets. Pathogenic Escherichia coli, including ETEC, use the...

BACKGROUND Enterotoxigenic Escherichia coli (ETEC) is an important pathogen that causes childhood and travelers' diarrhea. Here, we present the draft genomes of four ETEC isolates recovered from stool specimens of patients with diarrhea in Beijing, China and Dhaka, Bangladesh, respectively. RESULTS We obtained the draft genomes of ETEC strains CE516 and CE549 isolated in China, and E1777 and ...