The bovine pre-implantation embryo secretes bioactive molecules from early development stages, but effects on endometrial function are reported to start only after elongation. Here, we interrogated spatially defined regions of the endometrium transcriptome for responses to a day 7 embryo in vivo. We hypothesize that exposure to an embryo changes the abundance of specific transcripts in the cran...

endometrial calcification along with ossification is an uncommon clinical entity. most of the cases are asymptomatic or present with secondary infertility. endometrial ossification associated with repeated abortions has been reported very infrequently. here we report a case of endometrial calcification with ossification  due to retained fetal bony tissue in a 38 year old symptomatic female havi...

10 INTRODUCTION 12 REVIEW OF THE LITERATURE 13 1 Epigenetics overview 13 1.1 DNA methylation 14 1.2 Post-translational histone modifications and chromatin remodeling 16 1.3 Noncoding RNAs and RNA interference 17 1.4 Interplay between different epigenetic factors 18 1.5 Epigenetic inheritance 19 2 Basic characteristics of cancer 20 3 Cancer genetics 23 3.1 Tumor suppressor genes 23 3.2 Oncogenes...

PURPOSE A recent landmark study demonstrated that Dichloroacetate (DCA) treatment promoted apoptosis in lung, breast, and glioblastoma cancer cell lines by shifting metabolism from aerobic glycolysis to glucose oxidation coupled with NFAT-Kv1.5 axis remodeling. The objective of this study was to determine whether DCA induces apoptosis in endometrial cancer cells and to assess apoptotic mechanis...

micrornas participate in the regulation of asthma, the goal of this study is to summarize recent researches on the roles of micrornas in the pathogenesis of asthma. a review of the english medical literatures was conducted by searching pubmed for studies concerning asthma and micrornas. the results of the present study indicate that micrornas play important roles in regulating asthma immune res...

objective: in order to evaluate the endometrium by ultrasound in patients undergoing controlled ovarian hyperstimulation (coh) with clomiphene citrate (cc) and human menopausal gonadotropin (hmg) with intrauterine insemination (iui) to determine the relationship between endometrial pattern and thickness on pregnancy rate (pr). methods: in this prospective study, 108 infertile couples underwent ...

objective: the endometrial hyperplasia measured by ultrasound in polycystic ovary syndrome (pcos) women is strongly related to pathologic endometrial thickness, but there is no consensus on the relation between serum luteinizing hormone (lh) and either of these factors: pathologic endometrial hyperplasia and body mass index (bmi). materials and methods: in this observational cross-sectional stu...

background uterine cancer stays the most prevalent gynecologic malignancy in developed countries. providing suitable solutions to treat this disease is required to the early diagnosis of this cancer. objectives the aim of this study was to evaluate the effectiveness of multiple-site lymph node sampling in patients with the endometrioid type of endometrial cancer. patients and methods demographi...

background: transvaginal ultrasound is one of the most common means to examine endometrial cavity lesions although its negative results are more valuable. saline sonohysterography can reduce the number of false negative rates of endometrial lesions diagnoses in tamoxifen consumers. the objective of this study was to determine the diagnostic values of saline infusion sonohysterography (sis) and ...