thymol, an important and advantageous component of many essential oils, has been applied as an antimicrobial agent in animals. to increase the duration of action of this compound in ruminants, it was decided here to prepare a controlled release carrier for thymol. hydroxy propyl methyl cellulose (hpmc) and ethyl cellulose (ec) were used as the matrix polymer here. mixtures of thymol with eight ...

This research describes the role of starch nanoparticles in stabilizing surfactant-free emulsion, namely Pickering emulsion. However, concentration and NaOH during preparation as a emulsifier have not been studied. Thus, this study aimed to obtain proper concentrations when preparing breadfruit-based emulsifiers for varied (1, 3,or 5 (%(w/v)) (0.1875 0.375 M) form dispersion. Starch were acquir...

Purpose: Ofloxacin is a fluoroquinolone with broad-spectrum antibacterial action, used in treatment of systemic and local infections. Ofloxacin is BCS class II drug having low solubility, high permeability with short half-life. The present work was aimed to design, develop and optimize gellified emulsion of Ofloxacin to provide site targeted drug delivery. Transdermal drug delivery will enhance...

Objective(s) Theophylline, a xanthenes derivative, is still widely used as an effective bronchodilator in the management of asthmatic patients. It is used both as a prophylactic drug and to prevent acute exacerbations of asthma. The aim of study was to formulate and evaluate effect of the microencapsulation of theophylline loaded nanoparticles on the reduction of burst release. Materials and Me...

Insulin-loaded PEG2-PLA40 and PEG5-PLA20 microspheres containing 5% bovine insulin were manufactured using single emulsion and w/o/w multiple emulsion-solvent evaporation techniques. Microspheres were characterized for their insulin encapsulation efficiency and release characteristics in phosphate-buffered saline (PBS) at pH 7.4 and 37 ÂC. Moreover, the stability of the peptide during 18 days o...

the present study involves preparation and evaluation of gastric-mucoadhesive microparticles with metformin hydrochloride as model drug for prolongation of gastric residence time. the microparticles were prepared by the emulsification solvent evaporation technique using polymers of carbomer 934p (c) and ethylcellulose (ec). the microparticles were prepared by emulsion solvent evaporation method...

In this paper, a new robust ESD protection structure has been proposed for smart power technology. By inserting a P+ diffusion into the drain region of 40VLDMOS power transistor, the embedded SCR (ESCRLDMOS) device can be built and without changing any DC I-V characteristics of a 40V-LDMOS power transistor. It is also found that the method with P+ strap inserted into drain region (N+ in NW) can...