OBJECTIVE To investigate the effect of combined prophylactic ramosetron and total intravenous anaesthesia (TIVA) on postoperative nausea and vomiting (PONV), compared with sevoflurane anaesthesia without prophylactic antiemetics, in female patients undergoing thyroidectomy. METHODS Female patients were randomized between the sevoflurane group (anaesthesia maintained with sevoflurane) or TIVA ...


 Pregnancy is a condition that causes physical and psychosocial changes in woman due to the growth development of her reproductive organs fetus. Many factors influence pregnancy from inside as well outside can cause problems, especially for first time pregnant. According Anwar, doctors at Bunda Jakarta Hospital around 50-70% pregnant women experience it said normal 8-12 weeks gradually de...

BACKGROUND In the US, noroviruses are estimated to cause 21 million cases annually with economic losses reaching $2 billion. Outbreak investigations frequently implicate vomiting as a major transmission risk. However, little is known about the characteristics of vomiting as a symptom or the amount of virus present in emesis. METHODOLOGY AND PRINCIPAL FINDINGS Emesis samples and symptomology d...

The use of glucagon-like peptide-1 (7-36) amide (GLP-1) receptor agonists for the treatment of type 2 diabetes mellitus is commonly associated with nausea and vomiting. Therefore, the present studies investigated the potential of GLP-1 receptor ligands to modulate emesis and feeding in Suncus murinus. Exendin-4, a selective GLP-1 receptor agonist, was administered subcutaneously (1-30 nmol/kg) ...

CONTEXT Postoperative emesis is common after pyloromyotomy. Although postoperative feeding is likely to be an influencing factor, there is no consensus on optimal feeding. OBJECTIVE To compare the effect of feeding regimens on clinical outcomes of infants after pyloromyotomy. DATA SOURCES Cumulative Index to Nursing and Allied Health Literature, The Cochrane Central Register of Controlled T...

V OMITING is a complicated act which involves the coordinated activities of many motor systems of the body including both the somatic and autonomic nervous outflows. The orderly sequential action of the different muscle groups used in emesis has been clearly demonstrated by the now classical work of Cannon (I). Equally complex is the question of the sensory pathways of vomiting. The roles of th...

Clinical utility of phosphodiesterase 4 (PDE4) inhibitors as anti-inflammatory agents has, to date, been limited by adverse effects including nausea and emesis, making accurate assessment of emetic versus anti-inflammatory potencies critical to the development of inhibitors with improved therapeutic indices. In the present study we determined the in vitro and in vivo anti-inflammatory potencies...

Signals from the vestibular system, area postrema, and forebrain elicit nausea and vomiting, but gastrointestinal (GI) vagal afferent input arguably plays the most prominent role in defense against food poisoning. It is difficult to determine the contribution of GI vagal afferent input on emesis because various agents (e.g., chemotherapy) often act on multiple sensory pathways. Intragastric cop...