We describe the elt-4 gene from the nematode Caenorhabditis elegans. elt-4 is predicted to encode a very small (72 residues, 8.1 kD) GATA-type zinc finger transcription factor. The elt-4 gene is located approximately 5 kb upstream of the C. elegans elt-2 gene, which also encodes a GATA-type transcription factor; the zinc finger DNA-binding domains are highly conserved (24/25 residues) between t...

The Caenorhabditis elegans GATA transcription factor elt-1 has previously been shown to have a central role in the specification of hypodermal (epidermal) cell fates and acts several cell divisions before the birth of hypodermal cells. Here we report that elt-1 also has essential functions during subsequent development. Reporter gene studies show that elt-1 expression is maintained in lateral s...

Adopting the critical discourse analysis framework, in general, andFairclough’s (1989) critical text analysis, in particular, the current study aims atexamining 3 aspects of meaning, namely social relations, subject positions, andcontents in the conversation as well as vocabulary and grammar parts of Passages 1(an American textbook) and First Certificate (a British textbook) to find out whether...

This paper presents a part of an on-going project that aims at developing an instrument to evaluate English language teaching textbooks, called the English Language Teaching (ELT) Textbook Evaluation Checklist. The present study sought to evaluate the validity, reliability and economy of the developed checklist. It also aimed to find out to what extent the users of the checklist were satisfied ...

One of the most problematic issues in ELT textbooks used public secondary schools Turkey is their inability to reflect active practice principles action-oriented approach, which Turkish curriculum for primary and claims have adopted. The textbooks, thus, are inefficient, not mention inadequate, train social actors, a goal set by Common European Framework Reference Languages (CEFR). This paper c...

Interlanguage pragmatics, as an inseparable part of communicative competence, has been emphasized as an ultimate objective in language learning. This study explored the perceptions of Iranian English as a foreign language (EFL) students regarding interlanguage pragmatics and the impact of textbooks tasks on shaping their pragmatic competence. To accomplish this objective, 137 senior EFL student...

Eltrombopag (ELT) is a novel thrombopoietin receptor agonist for the treatment of idiopathic thrombocytopenic purpura. Previous reports indicate that ELT is mainly eliminated in the liver, although its pharmacokinetic profile has not yet been clarified in detail. The purpose of the present study is to investigate the overall elimination mechanism of ELT. After intravenous administration of ELT ...

Self-assessment and peer-assessment have been appraised in a large number of studies, aiming at investigating their effectiveness in different contexts. However, the challenges of implementing self-assessment and peer-assessment have been investigated rather sporadically. Given that, the purpose of this study was to explore the challenges and probable solutions of implementing self-assessment a...