normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : cotoneaster discolor and alhagi pseudalhagi are two important kinds of iranian manna.   they have several therapeutic applications in adults and children. the most important ingredient of cotoneaster discolor is mannitol. due to the scarcity of toxicological studies on these compounds, their genotoxicity was e...

background: early pleural tuberculosis (tb) diagnosis is particularly difficult. the aim of this study was to investigate the diagnostic accuracy of the xpert mtb/rif (xpert) (cepheid, sunnyvale, ca) assay using pleural biopsy and pleural fluid specimens in patients with suspected pleural tb but who had a negative sputum acid-fast bacilli (afb) smear. materials and methods: in this study, 134 s...

abstractbackground: radioprotective effects of famotidine, an antagonist of h2 receptor clinically used for peptic ulcer treatment, was previously shown on radiation-induced micronuclei and chromosomal aberration in human peripheral blood lymphocytes and mouse bone marrow cells. this study was conducted to investigate radioprotective property of famotidine against radiation induced apoptosis in...

introduction: this study aimed to compare the cytotoxicity of mta fillapex, ah-26 and apatite root canal sealers at different times after mixing. methods and materials: in this in vitro study, mta fillapex, ah-26 and apatite root canal sealer were spilled uniformly by 40 µm mesh in a 96-well plate. then, human fetal foreskin fibroblast cell line (hfff2) were added to each sealer cell culture me...

doxorubicin is a broad spectrum antibiotic used in the treatment of cancers. its dose dependent cardiotoxicity is the most serious side effect causing withdrawal of drug from hard chemotherapeutic regimen. statins are shown to be cytotoxic in concentrations higher than the effective doses for the treatment of hypercholesterolemia (40 mg/day). co-administration of statins and chemotherapeutic ag...

background cancer is one of the leading causes of human death. the discovery of new generations of low-cost anticancer drugs with high efficacy and low toxicity is necessary, and is only possible by screening medicinal plants with prior knowledge. objectives in this study, the bioactivities of three medicinal plants from india, including alstonia scholaris, alstonia venenata, and moringa oleife...

mucopolysaccharidoses are a group of rare mostly autosomal recessive metabolic and genetic disorders. because of the high rate of consanguinity, they are not uncommon in our population. clinical diagnosis is not difficult for experienced physicians, but it is not enough for treatment and prevention measures in the future pregnancies. so, it is necessary to detect the type of mps by measurement ...

Background: Globozoospermia is an uncommon disorder of sperm morphology associated with severe male infertility. Patients who contain both normal and round-headed sperm are called partial globozoospermic. It is possible that round-headed sperm may have an abnormal chromatin structure and /or DNA strand breaks. Moreover, sperm DNA fragmentation and protamine deficiency is shown to be associated ...