نتایج جستجو برای: eliza avidity

تعداد نتایج: 3917  

Journal: :The Journal of Experimental Medicine 1974
Michael H. Julius Leonard A. Herzenberg

Cells binding DNP groups conjugated to fluoresceinated mouse gamma globulin ((F)DNP-MGG) were isolated from spleens of unprimed mice using a fluorescence-activated cell sorter (FACS). The isolated cells were specifically enriched at least 100-fold for anti-DNP precursor activity in an adoptive transfer assay as compared to unfractionated spleen. The fraction depleted of binding cells, although ...

Dear Editor: At reviews in my research field, faced to an article published in your journal in Volume 20, Number 106, April 2013 titled "avidity ELISA method in the diagnosis of congenital toxoplasmosis", with interest all looked at it and found we had vague hints as to help promote your Journal referred to them. As you know, the purpose of this study was to determine the prevalence P...

Journal: :Revista do Instituto de Medicina Tropical de Sao Paulo 1999
M Villavedra J Battistoni A Nieto

We describe the avidity maturation of IgGs in human toxoplasmosis using sequential serum samples from accidental and natural infections. In accidental cases, avidity increased continuously throughout infection while naturally infected patients showed a different profile. Twenty-five percent of sera from chronic patients having specific IgM positive results could be appropriately classified usin...

2013
Jacob Konikoff Ron Brookmeyer Andrew F. Longosz Matthew M. Cousins Connie Celum Susan P. Buchbinder George R. Seage Gregory D. Kirk Richard D. Moore Shruti H. Mehta Joseph B. Margolick Joelle Brown Kenneth H. Mayer Beryl A. Koblin Jessica E. Justman Sally L. Hodder Thomas C. Quinn Susan H. Eshleman Oliver Laeyendecker

BACKGROUND A limiting antigen avidity enzyme immunoassay (HIV-1 LAg-Avidity assay) was recently developed for cross-sectional HIV incidence estimation. We evaluated the performance of the LAg-Avidity assay alone and in multi-assay algorithms (MAAs) that included other biomarkers. METHODS AND FINDINGS Performance of testing algorithms was evaluated using 2,282 samples from individuals in the U...

شریعت بهادری1, احسان, صدرایی1, جاوید, موسوی پور2 , سیده سمیه ,

Background and purpose: One of the transmission ways of the congenital toxoplasmosis is through the placenta to the fetus, therefore, its diagnosis at early stage is very important. Toxoplasma gondii parasite contains various antigens of which excretory-secretory antigens (E/SA) are used in designing Elisa avidity kit. The aim of this study was to compare the results of commercial kit and desig...

2012
Vivian L. Weiss Timothy H. Lee Hong Song Theodore S. Kouo Chelsea M. Black George Sgouros Elizabeth M. Jaffee Todd D. Armstrong

BACKGROUND Cancer vaccines are designed to activate and enhance cancer-antigen-targeted T cells that are suppressed through multiple mechanisms of immune tolerance in cancer-bearing hosts. T regulatory cell (Treg) suppression of tumor-specific T cells is one barrier to effective immunization. A second mechanism is the deletion of high avidity tumor-specific T cells, which leaves a less effectiv...

Journal: :Clinical and diagnostic laboratory immunology 1999
M Paul

Traditional serological techniques have some limitations in evaluating the duration of Toxoplasma gondii infection in pregnant women, patients with lymphadenopathy, and older children suspected of having congenital toxoplasmosis. In these three groups of patients, two variants of T. gondii immunoglobulin G (IgG) avidity tests were used: an EIA Kit (Labsystems) and a noncommercial enzyme-linked ...

Journal: :Journal of virology 2014
Zhidong Hu Jing Wang Yanmin Wan Lingyan Zhu Xiaonan Ren Sugan Qiu Yanqin Ren Songhua Yuan Xiangqing Ding Jian Chen Chenli Qiu Jun Sun Xiaoyan Zhang Jim Xiang Chao Qiu Jianqing Xu

UNLABELLED T-cell functional avidity is a crucial determinant for efficient pathogen clearance. Although recombinant DNA priming coupled with a vaccinia-vectored vaccine (VACV) boost has been widely used to mount robust CD8+ T-cell responses, how VACV boost shapes the properties of memory CD8+ T cells remains poorly defined. Here, we characterize the memory CD8+ T cells boosted by VACV and demo...

Journal: :Thorax 1999
O Ciofu T D Petersen P Jensen N Høiby

BACKGROUND In order to study the impact on the lung function of patients with cystic fibrosis of the avidity of antipseudomonal antibodies, the avidity of antibodies against the chromosomal beta-lactamase of Pseudomonas aeruginosa (a beta ab) and against the 60-65 kDa heat shock protein of P aeruginosa (anti-GroEL) were measured in serum samples collected longitudinally during chronic infection...

Journal: :Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 2017
Libuse Noskova Lenka Fialova Ales Bartos Tomas Zima

AIMS To optimise the ELISA method for the avidity of IgG antibodies against neurofilament heavy chain (NfH) and to determine the levels and avidity of anti-NfH antibodies in patients with Alzheimer's disease (AD) and a healthy control group. METHODS Various dilutions of sera and concentrations of urea and sodium chloride as chaotropic reagents were tested in the process of the ELISA optimisat...

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