For achieve sensitivity in lab-on-a-chip electrochemical detection, more reliable probing methods are required, especially for repeated measurements. Spring-probes are a promising candidate method which can replace needle-like probes and alligator clips that usually produce scratches on the surface of gold electrodes due to the strong physical contacts needed for electrochemical measurements. T...

A highly sensitive and selective method for amplified electrochemical detection for hairpin-stem-loop structured target sequences was developed based on the temperature regulation of DNA hybrids on a sandwich-type electrochemical DNA sensor. Multistep hybridization was applied to promote the hybridization efficiency of each section of sandwich structure. The results showed that both multistep a...

An electrochemical biosensor based on sulfonated graphene/polyaniline nanocomposite was developed for urea analysis. Oxidative polymerization of aniline in the presence of sulfonated graphene oxide was carried out by electrochemical methods in an aqueous environment. The structural properties of the nanocomposite were characterized by Fourier-transform infrared, Raman spectroscopy, X-ray photoe...

The first part of this research involves the development of a gold-nanoparticle based sandwich type immunosensor to identify trace amounts of human chorionic gonadotropin hormone based on the direct electrochemical detection of Au nanoparticles. The second part of this research is to design a biosensor that can be easily handled, has higher specificity, sensitivity, low-cost, and rapid response...

Modification of carbon materials, especially graphene-based materials, has wide applications in electrochemical detection such as electrochemical lab-on-chip devices. A glassy carbon electrode (GCE) modified with chemically alternated graphene oxide was used as a working electrode (glassy carbon modified by graphene oxide with sulphur containing compounds and Nafion) for detection of nucleobase...

A novel ferrocene-derived substrate for the ratiometric electrochemical detection of alkaline phosphatase (ALP) was designed and synthesised. It was demonstrated to be an excellent electrochemical substrate for the ALP-labelled enzyme-linked immunosorbent assay (ELISA).

An electrochemical DNA detection format has been developed to allow simple and rapid assays with downsized instruments. Since naphthalene diimide derivatives are known to bind to double stranded DNA (dsDNA) with threading intercalation, they are stabilized by pseudo-catenane formation. For example, ferrocenylnaphthalene diimide (FND) can be efficiently concentrated on dsDNA, thus enabling its...

Soil testing is the basis for nutrient recommendation and formulated fertilization. This study presented a brief overview of potentiometric electrochemical sensors (ISE and ISFET) for soil NPK detection. The opportunities and challenges for electrochemical sensors in soil testing were

the combination of graphene (gr) and nickel oxide nanoparticles (nio nps) yields nanostructured electrochemical sensor formed a novel kind of structurally uniform and electrocatalytic activity material. in cyclic voltammetry (cv) studies, in the presence of ep, nio/gr composite modified electrode shows a significantly higher current response for ep oxidation. based on differential pulse voltamm...

In this study, the novel surface ion-imprinted polymer (IIP) particles were prepared and applied as a electrode modifier in stripping voltammetric detection of lead(II) ion. A carbon paste electrode (CPE) modified with IIP nanoparticles and multi-walled carbon nanotubes (MWCNTs) was used for accumulation of toxic lead ions. Various factors that govern on electrochemical signals including carbon...