In patients with chronic hepatitis and continuous inflammation of the liver, fibrosis develops during the course of wound healing, and with recurrent accumulation of scar tissue and regenerative nodular formation, chronic hepatitis progresses to cirrhosis. In untreated patients with chronic hepatitis C infection, which is a leading cause of hepatocellular carcinoma (HCC), the Metavir liver fibr...

The presence of significant fibrosis is an indicator for liver disease staging and prognosis. The aim of the study was to determine reproducibility of real-time shear wave elastography using a hepatic biopsy as the reference standard to identify patients with chronic liver disease. Forty patients with chronic liver disease and 12 normal subjects received shear wave elastography performed by ski...

BACKGROUND Liver fibrosis is a sign of advanced liver disease and is often an indication for treatment. The current standard for diagnosing liver fibrosis and steatosis is biopsy, but noninvasive alternatives are available; one of the most common is transient elastography (FibroScan). OBJECTIVES The objective of this analysis was to assess the diagnostic accuracy and clinical utility of trans...

The clinical feasibility of 2D elastography methods is hindered by the requirement that the operator avoid out-of-plane motion of the ultrasound image during palpation, and also by the lack of volumetric elastography measurements. In this paper, we develop and evaluate a 3D elastography method operating on volumetric data acquired from a 3D probe. Our method is based on minimizing a cost functi...

A low cost, quasi real-time elastography system, displacement-gradient elastography (DGE), was developed by applying digital image correlation (DIC) method and smoothing algorithm to B-mode ultrasound images. In order to achieve quasi real-time elastogram display, a new fast pattern matching algorithm, decoupled cross-correlation (DCC), was proposed and validated. By applying the DGE to various...

Elastography is a non-invasive medical imaging technique that detects tumors based on their stiffness (elasticity) compared to normal tissue. The most common type of elastography uses ultrasonic imaging to compare the shapes of the tissue under examination before and after it is compressed slightly. Cancerous tumors tend to be many times stiffer than normal tissue, which "gives" under compressi...

In patients with chronic hepatitis and continuous inflammation of the liver, fibrosis develops during the course of wound healing, and with recurrent accumulation of scar tissue and regenerative nodular formation, chronic hepatitis progresses to cirrhosis. In untreated patients with chronic hepatitis C infection, which is a leading cause of hepatocellular carcinoma (HCC), the Metavir liver fibr...

Palpation of organs is one of the oldest clinical examination techniques, for instance, if you think of the palpation of the breast or the digital rectal examination of the prostate, where hard palpable regions are suspicious for cancer. This is the basic principle of real-time elastography, an ultrasound technique, which is able to visualise tissue elasticity. Since prostate cancer features an...

In the last decade, ultrasound elastography, an already widely used technique in the diagnosis of hepatic fibrosis, has raised the attention of nephrologists as a potential valuable noninvasive tool for the diagnosis of renal fibrosis. Due to renal deep location and anatomic complexity, the shear wave techniques are the most appropriate elastography methods for exploring native kidneys. Recent ...

Elastography is an imaging modality for the evaluation of tissue stiffness, which has been used for the analysis of superficial organs, such as those of the breast and prostate. The measurement of tissue elasticity has been reported to be useful for the diagnosis and differentiation of tumors, which are stiffer than normal tissues. Endoscopic ultrasonography elastography (EUS-EG) is a promising...