Wide local excision followed by external beam radiation therapy (EBRT) to the whole breast has become the standard of care for most patients with localised 'early' breast cancer in the UK, Europe, and the USA. Local relapse rates are low, and overall survival figures have improved during the past decade, with the advent of more effective systemic endocrine- and chemo-therapy. A policy of EBRT f...

BACKGROUND We reviewed the outcomes of oropharyngeal squamous cell carcinoma treated with external beam radiation and interstitial brachytherapy. METHODS Ninety patients with squamous cell carcinoma of the oropharynx were treated with interstitial brachytherapy at the University of Utah between 1984 and 2001. Seventy-two patients received external beam radiotherapy (EBRT) followed by brachyth...

Treatment of cervical cancer includes combination of external beam radiation therapy (EBRT) and brachytherapy (BRT). Traditionally, coronal images displaying dose distribution from a ring and tandem (R&T) implant aid in construction of parametrial boost fields. This research aimed to evaluate a method of shaping parametrial fields utilizing contours created from the high-dose-rate (HDR) BRT dos...

BACKGROUND Patients with early stage prostate cancer have a variety of curative radiotherapy options, including conventionally-fractionated external beam radiotherapy (CF-EBRT) and hypofractionated stereotactic body radiotherapy (SBRT). Although results of CF-EBRT are well known, the use of SBRT for prostate cancer is a more recent development, and long-term follow-up is not yet available. Howe...

The latter 2 decades of the last century have witnessed significant improvements in external beam radiotherapy (EBRT), moved primarily by the advances in imaging modalities and computer-based treatment planning. These advancements lead to introducing the addition of a fourth-dimension, time, to the three-dimensional geometry in EBRT. The new era in EBRT presents challenges and opportunities to ...

BACKGROUND Prostate cancer is the most common cancer in males in the UK and affects around 105 men for every 100,000. The role of radiotherapy in the management of prostate cancer significantly changed over the last few decades with developments in brachytherapy, external beam radiotherapy (EBRT), intensity-modulated radiotherapy (IMRT), and image-guided radiotherapy (IGRT). One of the challeng...

The effects of Tween-20 and Zn(II) on ethylbenzene removal were evaluated using two biotrickling filters (BTFs), BTF1 and BTF2. Only BTF1 was fed with Tween-20 and Zn(II). Results show that ethylbenzene removal decreased from 94% to 69% for BTF1 and from 74% to 54% for BTF2 with increased organic loading from 64.8 to 189.0 g ethylbenzene/(m³·hr) at EBRT of 40 sec. The effect of EBRT (60-15 sec)...

In conclusion, although surgery remains the first choice to treat ROLC, a considerable number of patients are inoperable. EBRT is an alternative, but is hampered since the ROLC is effectively invisible. We report that the use of metallic clips placed during bronchoscopy can make ROLC visible for the radiation oncologist. The clips appear to be safe, well tolerated and removable in inoperable pa...

PURPOSE The European Organisation for Research and Treatment of Cancer (EORTC) trial 22991 ( NCT00021450 ) showed that 6 months concomitant adjuvant androgen suppression (AS) improves event- (EFS, Phoenix) clinical disease-free survival (DFS) intermediate- high-risk localized prostatic carcinoma, treated by external-beam radiotherapy (EBRT) at 70-78 Gy. We report the long-term results in interm...