Persistent severe inflammation in colonic mucosa is thought to cause the development of colon cancer in patients with ulcerative colitis (UC). However, predisposing genetic abnormalities have not been identified in this sequence. Using differential display PCR, we isolated cDNA fragments corresponding to mRNAs that were differentially expressed in colitis-associated cancer tissues and mucosa wi...

Objective. To determine the long-term histopathologic changes in nasal mucosa and the relationship between progression of the histopathologic changes and the duration without air current stimulation. Material and Method. Biopsies were taken from the inferior turbinates of 11 laryngeal cancer patients after total laryngectomy. Specimens were stained with hematoksilen-eosin and several histopatho...

PURPOSE The purpose of this study was to determine the effect of number of chewing strokes on change in blood flow in denture-supporting maxillary mucosa. METHODS Subjects consisted of 11 healthy dentate men. Mastication was simulated by intermittent loading (10 N, 1/0.75 Hz) on a lateral area of the hard palate using a 2-cm(2) test plate. Loading duration was set at 1, 4, 8 or 12 min (80, 32...

BACKGROUND AND AIM: This study evaluated the quality of life (QOL) of patients with diseases of oral mucosa referred to Kerman Dental School, Kerman, Iran during 2014-2015.METHODS: Total of 101 patients seen in the Kerman Department of Oral Medicine with chronic oral mucosal diseases were included in the study. They completed the designed questionnaire to assess their QOL. After the final edit,...

mast cells are related to certain gastrointestinal complaints. mast cell density has not been studied in cardio-esophageal region to the best of our knowledge. in this study we wanted to obtain an estimate of mast cell density in this region and compare it with mast cell density in antrum. from april 2007 till march 2010, we chose children (<14 years old) who underwent upper endoscopy and from ...

E4 CUTIS WWW.CUTIS.COM To the Editor: A 34-year-old woman presented for evaluation of dry mouth and painless peeling of the oral mucosa of 2 months’ duration. She denied any other skin eruptions, dry eyes, vulvar or vaginal pain, or recent hair loss. A recent antinuclear antibodies test was negative. The patient’s medical history was otherwise unremarkable and her current medications included m...

objective: to identify the proportion and some selected characteristics of juvenile diabetics attending birdem hospital. materials and methods: this was a cross sectional study. the study was conducted in the birdem hospital. all diabetic young aged up to 18 years who visit birdem hospital were included in study population. the sample size was 240. results: it was observed that among the respon...

Background and Objectives: Primary acquired nasolacrimal duct obstruction (PANDO) is a common ocular problem. Clinical presentation can range from simple tearing to a life-threatening condition. The exact pathophysiology of obstruction is not completely understood. In this study, therelationship between PANDO and nasal mucosal goblet cells was investigated.  Materials & Methods: In this case-c...