in order to investigate the effect of adding fennel powder (foeniculum vulgare) in starter diet on performance, immunity system and biometric parameters of holstein calves, 30 holstein calves (15 males and 15 females) with birth weight of 40±0.5 kg were used in a completely randomized design. experimental diets were: 1. starter without fennel powder (control), 2. starter containing 0.4% fennel ...

se of freeze granulated powders is successfully used as an industrially viable alternative to loose powder sintering for transparent polycrystalline lumina (PCA). Freeze granulation with narrow granule size distribution was realized after suspension condition optimization, with very good owability and regular spherical shapes. The key factors are low viscosity slurries linked to the complex int...

Pulmonary drug delivery of ciprofloxacin hydrochloride offers effective local antibacterial activity and convenience of easy application. Spray drying is a trustworthy technique for the production of ciprofloxacin hydrochloride microparticles. Quality by design (QbD), an up-to-date regulatory-based quality management method, was used to predict the final quality of the product. According to the...

Dry powder formulations are often composed of fi ne drug particles and coarser carrier particles, typically -lactose monohydrate because it is an inert, cheap, broadly available and non-toxic excipient1. However, the effi ciency of a powder formulation may be highly dependent on the lactose quality and source2. Indeed, interactions between particles are mainly dependent on the physicochemical c...

The aim of this study was to design, develop, and optimize respirable tacrolimus microparticles and nanoparticles and multifunctional tacrolimus lung surfactant mimic particles for targeted dry powder inhalation delivery as a pulmonary nanomedicine. Particles were rationally designed and produced at different pump rates by advanced spray-drying particle engineering design from organic solution ...