Background: Prisoners, compared to the general population, are at greater risk of infection. Drug injection is the main route of HIV transmission, in particular in Iran. What would be of interest is to determine variables that govern drug injection among prisoners. However, one of the issues that challenge model building is incomplete national data sets. In this paper, we addressed the process ...

My summer research project as an REU student at UC Davis has mainly been an effort to create and motivate methods to achieve high-throughput screening of biomolecules from the National Cancer Institute (NCI) as possible treatments for various types of cancer. The hope of my advisor, Dr. Xiang Dong Zhu, and the rest of his group is to offer a competitive label-free drug screening technique to th...

The American College of Surgeons Committee on Trauma (ACS/COT) has mandated alcohol screening and brief intervention (SBI) for all level-I trauma centers. Few investigations have assessed alcohol and drug comorbidity among patients receiving mandated alcohol SBI at trauma centers. In this study, 878 randomly selected level-I trauma center inpatients were systematically screened for alcohol and ...

BACKGROUND The objective of this study was to identify high-yield screening risk factors for detecting maternal non-medical drug use during pregnancy. METHODS A four year retrospective analysis was conducted at an academic medical center. Detailed chart review of both the newborn and mother's medical record was performed on all cases for which one or more drug(s) or metabolite(s) were identif...

Background Unhealthy drug use (UDU), including both illicit drug use and misuse of prescription medications, is high among Americans 12 or older (9.4% past month; 48% lifetime), and is often 50-100% higher among emergency department (ED) patients (Cherpitel & Ye, 2008). While most screening, brief intervention and referral to treatment (SBIRT) projects focus on questionnaire screening for UDU, ...

I modified a procedure for screening urine specimens for evidence of drug abuse, to permit direct use of commercially available ion-exchange papers in hemagglutination-inhibition assay for drug detection. Small circles punched out of the papers, which previously had been impregnated with drug-containing urine, were used in the detection step, leaving the remainder of the specimens on paper avai...

Effective treatments extend lives in the world, and significant efforts are in place to expand the use of life-saving medications in the developing world. This paper gives an overview of drug discovery process and emphasises in the area of virtual screening. Because machine learning is fast becoming a popular mechanism to support activity recognition in drug discovery process and other real-wor...

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to evaluate off-label and off-nccn guidelines uses of antineoplastic drugs in a major chinese hospital.totally 1122 patients were selected from july to december 2011. then, the off-label and off-nccn guidelines uses of antineoplastic drugs were analyzed.in 798 of 1122 patients (71.12%), drugs were used for off-label. in 317 of 1122 patients (28.25%), the drugs were prescribed for off-label and ...