نتایج جستجو برای: drug screening

تعداد نتایج: 795174  

Journal: :JNCI: Journal of the National Cancer Institute 1996

Journal: :Applied sciences 2021

The up-and-coming microfluidic technology is the most promising platform for designing anti-cancer drugs and new point-of-care diagnostics. Compared to conventional drug screening methods based on Petri dishes animal studies, delivery in systems has many advantages. For instance, these platforms offer high-throughput screening, require a small number of samples, provide an vivo-like microenviro...

2012
Takuya Chiba Tomoshi Tsuchiya Ryoichi Mori Isao Shimokawa

Recent drug discovery efforts have utilized high throughput screening (HTS) of large chemical libraries to identify compounds that modify the activity of discrete molecular targets. The molecular target approach to drug screening is widely used in the pharmaceutical and biotechnology industries, because of the amount of knowledge now available regarding protein structure that has been obtained ...

2016
Zhuofa Chen Weizhi Li Gihoon Choi Xiaonan Yang Jun Miao Liwang Cui Weihua Guan

Microfluidics-based drug-screening systems have enabled efficient and high-throughput drug screening, but their routine uses in ordinary labs are limited due to the complexity involved in device fabrication and system setup. In this work, we report an easy-to-use and low-cost arbitrarily accessible 3D microfluidic device that can be easily adopted by various labs to perform combinatorial assays...

Journal: :SLAS DISCOVERY: Advancing the Science of Drug Discovery 2020

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