Isotherms of the binding of the anthracycIine antibiotic, adriamycin (adriblastin), to DNA histone complexes was studied by means of spectroscopic analysis. The results indicated that: (a) binding of adriamycin to histones reduced the interaction of histones with DNA, (b) binding of the drug to DNA did not change the binding affinity of histone to DNA and, (c) in the explored binding range...

Patient demand for esthetic dentistry with minimally invasive procedures has resulted in the extensive use of freehand bonding of composite resin to anterior teeth. Preservation of remaining tooth structure and using as much enamel to bond to have made the procedure very predictable. In order to achieve maximum esthetics, the dentist must be able to use multiple layers of composite to mimic too...

In addition to increasing the efficacy of various drugs, Nanoparticles reduce their side effects. In this study, different nanoparticle formulations of Doxorubicin anticancer drugs were prepared. The efficacy of the formulations produced in the cell culture medium was studied compared with the free drug. Reverse phase evaporation was used to form the liposome containing do...

A technique is described in which a polyester casting resin is used instead of agar for the growth of Neisseria gonorrhoeae in a biphasic system. In complex medium, higher concentrations and stability of T1 colony type were obtained with resin than with either agar or broth alone after 24 h of incubation. In defined medium, the growth of gonococci and colony type stability were similar in singl...

BACKGROUND AND AIM: Recurrent caries is defined as caries in the marginal edges of filled teeth and is the most common reason for restoration replacement. The aim of this study was to evaluation of recurrent caries in amalgam, resin-based restorations and crowns in bitewing radiographies in patients who attended Kerman dental radiology centers, Iran.METHODS: This cross-sectional study conducted...

This paper presents a systematic evaluation of a commercially available strontium-specific extraction chromatographic resin based on a crown ether (Sr spec ), for use in applications of Sr isotope ratio analysis dealing with samples displaying a complex and/or Ca-rich matrix composition. A protocol, consisting of (i) loading a sample digest in 7 M HNO3 onto the resin, (ii) rinsing the resin wit...

We recently utilized the technique of resin hemoperfusion (employing an Amberlite XAD-4 resin cartridge) to remove drug from a patient i deep coma after an estimated ingestion of greater than 4.5 grams of methaqualone. At plasma flow rates of 204 ml/min, the mean value for plasma clearance of methaqualone was 179 ml/min. The amount of methaqualone recovered from the cartridge at the end of the ...

Tests to determine the potential use of a quaternary ammonium resin-triiodide complex as a sterilizing agent showed that it was an ineffective sporicide and that bactericidal activity was impaired by complex milieu.

Preliminary work by paper and thinlayer chromatography have indicated the existence of a number of similar antagonists with different specific activity. In the earlier stage of the purification, it was studied whether the minor components were real or artifacts. We found it convenient to use buffered resin chromatography according to the procedure of Moore et al.2) for the separation of detoxin...

The purpose of this study was to use cation exchange resins mask Pregabalin's unpleasant taste. Dowex-50, a crosslinked polystyrene backbone, employed. DRCs were synthesised in batches with drug-to-resin ratios 1:1, 1:2, and 1:3. optimal ratio as well the time required for maximum complexation discovered. In work, an attempt made develop taste-masked Pregabalin solution using simple, rapid, cos...