BACKGROUND Adverse events related to drugs occur frequently among inpatients, and many of these events are preventable. However, few data are available on adverse drug events among outpatients. We conducted a study to determine the rates, types, severity, and preventability of such events among outpatients and to identify preventive strategies. METHODS We performed a prospective cohort study,...

In many real world applications, systematic analysis of rare events, such as credit card frauds and adverse drug reactions, is very important. Their low occurrence rate in large databases often makes it difficult to identify the risk factors from straightforward application of associations and sequential pattern discovery. In this paper we introduce a heuristic to guide the search for interesti...

Adverse drug events (ADEs) may cause serious injuries including death. Spontaneous reporting of ADEs plays a great role in detection and prevention of them, however, underreporting always exists. Although several interventions have been utilized to solve this problem, they are mainly based on experience and the rationale for choosing them has no theoretical base. The vast variety of behavioral ...

six months administration of bromocriptine mesylate significantly decreased glycated hemoglobin (hba1c), fasting blood sugar, postprandial blood sugar, and weight of 22 indian obese patients with type 2 diabetes mellitus with no serious adverse events. therefore, the novel mechanism of action, efficacy and acceptable safety profile makes this drug an attractive option for treatment of obese typ...

OBJECTIVES The aim of this study was to develop a strategy to identify adverse drug events associated with drug-drug interactions by analyzing the prescriptions of critically ill patients. METHODS This retrospective study included HIV/AIDS patients who were admitted to an intensive care unit between November 2006 and September 2008. Data were collected in two stages. In the first stage, three...

OBJECTIVES The purposes of this study were to develop a pediatric-focused tool for adverse drug event detection and describe the incidence and characteristics of adverse drug events in children's hospitals identified by this tool. METHODS A pediatric-specific trigger tool for adverse drug event detection was developed and tested. Eighty patients from each site were randomly selected for retro...

Introduction: Obstructive sleep apnea (OSA) is a highly prevalent sleep-disordered breathing (SDB).   Case Report: Two 53- and 51-year-old male cases with daytime sleepiness and opium abuse and severe sleep apnea and long respiratory events duration (200 and 275 seconds respectively) noted in polysomnography were reported at Ebn-e-Sina and Razavi hospita...

BACKGROUND Adverse drug events and medication errors are threats to quality care. Inpatient studies suggest that a pharmacist may reduce these events, but outpatient studies have not been forthcoming. METHODS We conducted a pooled analysis of 2 randomized controlled trials to determine the effect of pharmacist intervention on adverse drug events and medication errors. We studied 800 outpatien...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: pharmacovigilance assesses the safety profile of drugs. its main aim is the increase of spontaneous reporting of adverse drug reactions (adrs).the italian drug agency (aifa; agenzia italianadel farmaco) is financing several projects to the aim of increasing reporting, and in calabria a pharmacovigilance informa...