نتایج جستجو برای: drug distribution
تعداد نتایج: 1173770 فیلتر نتایج به سال:
evaluation and improvement of drug management process is essential for patient safety. the present study was performed whit the aim of assessing risk of drug management process in women surgery department of qeh using hfmea method in 2013. a mixed method was used to analys failure modes and their effects with hfmea. to classify failure modes; nursing errors in clinical management model, for cla...
the purpose of this study was to prepare and characterize nimodipine loaded microspheres using ethyl cellulose (ec) as a carrier polymer through an emulsion solvent evaporation method. these evaluations characterized the pattern of drug release from prepared microspheres. nimodipin loaded microspheres were prepared using an emulsification solvent evaporation method. the effect of process variab...
here, we report analysis of in vitro and in vivo drug release from an in situ formulation consisting of triamcinolone acetonide (tr) and poly(d,l-lactide-co-glycolide) (plga) and the additives glycofurol and hydroxyapatite nanoparticles (ha). we found that these additives enhanced drug release rate. we used the taguchi method to predict optimum formulation variables to minimise the initial burs...
Low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (LMWH-ISL-SLN) was developed for injective application. The morphological observation, particle diameter and zeta potential of LMWH-ISL-SLN were characterized using transmission electron microscopy (TEM) and a Malvern Zetasizer. Its entrapment efficiency (EE) and drug loading (DL) were determined by ultracen...
the aim of present study was to prepare gelatin nanoparticle for drug and gene delivery applications. these nanoparticles were prepared by two-step desolvation method. the body distribution of colloidal drug delivery systems was mainly influenced by two physicochemical properties namely particle size and surface characteristics. the influence of several factors on the fabrication process includ...
six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. blood samples were collected before and at various time intervals after the administration of the drug. serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. non...
Preparation and characterization of friendly colloidal Hydroxyapatite based on natural Milk’s casein
Biocompatible hydroxyapatite nanocomposites are biocompatible, biodegradable and nontoxic have been paid many attentions as one of the most suitable vehicle for drug delivery use. Our objective in this work was to prepare and characterize caseins based HA nanocomposite in a colloidal form for drug delivery purposes. Casein biopolymer was firstly extracted from skimmed milk by adding acetic acid...
Preparation and characterization of friendly colloidal Hydroxyapatite based on natural Milk’s casein
Biocompatible hydroxyapatite nanocomposites are biocompatible, biodegradable and nontoxic have been paid many attentions as one of the most suitable vehicle for drug delivery use. Our objective in this work was to prepare and characterize caseins based HA nanocomposite in a colloidal form for drug delivery purposes. Casein biopolymer was firstly extracted from skimmed milk by adding acetic acid...
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