The electronic circular dichroism (CD)-silent 2,5-bis(biphen-2-yl)terephthalaldehyde has been used as a sensor (reporter) of chirality for primary amines. through-space inductor–reporter interactions force change in the chromophore conformation toward one diastereomeric forms. structure reporter, with terminal flipping biphenyl groups, led to generating Cotton effects both lower- and higher-ene...
