BACKGROUND The benefits of intravenous tissue-plasminogen activator (tPA) in acute ischemic stroke are time-dependent. Emergency medical services (EMS) hospital prenotification of an incoming patient with potential stroke may provide a means of reducing evaluation and treatment times and improving treatment rates; yet, available data are limited. METHODS AND RESULTS We examined 371 988 patien...

BACKGROUND AND PURPOSE Despite quality improvement programs such as the American Heart Association/American Stroke Association Target Stroke initiative, a substantial portion of acute ischemic stroke patients are still treated with tissue-type plasminogen activator (alteplase) later than 60 minutes from arrival. This study aims to describe the documented reasons for delays and the associations ...

Endovascular recanalization for acute major cerebral artery occlusion is effective within a short time after symptom onset. However, its efficacy in the elderly remains unknown. We assessed the efficacy of our comprehensive stroke center's reduction of this time in 28 consecutive patients for elderly patients (defined as patients aged ≥75 years) with acute major cerebral artery occlusion treate...

Introduction/Objective. The outbreak of COVID-19 pandemic has posed major challenges to the process urgent care patients with acute ischemic stroke (AIS) that requires optimal and well-coordinated pre- in-hospital chains in order enable recanalization therapy commencement earliest possible. study?s objection was compare time-dependent performance measures treatment results AIS hospitalized at a...

BACKGROUND Prior studies demonstrated that patients with ST-segment-elevation myocardial infarction presenting during off-hours (weeknights, weekends, and holidays) have slower reperfusion times. Recent nationwide initiatives have emphasized 24/7 quality care in ST-segment-elevation myocardial infarction. It remains unclear whether patients presenting off-hours versus on-hours receive similar q...

Gender and Work Hours Transitions in Australia: Drop Ceilings and Trap-Door Floors We introduce the ideas of “drop ceilings”, that full-time employees who switch to reduced hours thereafter face an hours ceiling such that a return to full-time employment is difficult, and of “trap-door floors”, that full-time employees may be denied the opportunity to reduce their hours and instead face a choic...

Background We report the interim results of a process improvement initiative at comprehensive stroke center in which all tPA (tissue‐type plasminogen activator)–eligible patients were given tenecteplase for acute ischemic stroke. Methods retrospectively analyzed prospectively maintained single‐center registry consecutive with treated our emergency department or transferred further care. Patient...