The mechanism by which Haemophilus protects donor DNA from cellular restriction and degradative enzymes during transformation is unclear. In this report, we demonstrate that donor DNA enters Haemophilus influenzae through specialized membranous extensions, which we have termed "transformasomes." DNA within transformasomes is in a protected state--resistant to external DNase and cellular restric...

introduction: the main purpose of donor selection is not only the donor protection from blood donation complications but also the blood recipient not be expose to blood- transmitted diseases. this study aimed to determine the reason for exemption from donors among blood donor's who refer to ilam blood transfusion organization. materials and methods: this is a retrospective and descriptive ...

A series of donor-acceptor heteroleptic open sandwiches with formula CpM-M'Pyl (M = B, Al, Ga; M' = Li, Na; Cp = cyclopentadienyl; Pyl = pentadienyl) has been designed in silico using density functional theory. The most stable complexes are those containing boron as a donor atom. A molecular orbital analysis shows that the s character of the lone pair located at the group 13 element is mainly r...

Fermi-level pinning phenomena due to DX centers in AlGaAs/GaAs HEMT’s are analyzed using two-dimensional numerical simulation based on a drift-diffusion model. A DX center model is introduced assuming Fermi-Dirac statistics for ionized donor density with the aluminum mole fraction dependence of the deep-donor energy level. The calculated results reveal that the decrease in transconductance of A...

Spatial and dielectric confinement modulations of the spontaneous emission rates, transition energies, and charge-density distributions of a singly ionized double donor system D2 + in a spherical quantum dot are calculated within the framework of the effective-mass envelope function approximation. Dipole moments, energy splittings, transition moments, electron-density distributions, and spontan...

BACKGROUND Potential cardiac donors show various degrees of myocardial dysfunction, and the most severely affected hearts are unsuitable for transplantation. The cause of this acute heart failure is poorly understood. We investigated whether alterations in calcium-handling proteins, beta-adrenoceptor density, or the inhibitory G protein Gialpha could account for this phenomenon in unused donor ...

background and objectives: hepatitis e virus (hev) is a major public health concern in developing countries. hev transmission occurs primarily by the fecal-oral route. it has also been reported that blood donors are potentially able to cause transfusion-associated hepatitis e in endemic areas. this study aimed to determine the seroprevalence of hev infection among volunteer blood donors in cent...

AIMS Familial hypertrophic cardiomyopathy (HCM), frequently caused by sarcomeric gene mutations, is characterized by cellular dysfunction and asymmetric left-ventricular (LV) hypertrophy. We studied whether cellular dysfunction is due to an intrinsic sarcomere defect or cardiomyocyte remodelling. METHODS AND RESULTS Cardiac samples from 43 sarcomere mutation-positive patients (HCMmut: mutatio...

In this paper, NMR and QTAIM analysis for three substituted of T2SA complex was investigated in the gas and four solvents at DFT level. Intermolecular O–H…N hydrogen bonds between 1,2,4,5-Tetrazine and Sulphurous acids enhance the stability of complex.1,2,4,5-Tetrazine is a highly reactive diene for [4+2] inverse-Diels–Alder cycloaddition processes and an excellent precursor to attain the pyrid...

Background—Potential cardiac donors show various degrees of myocardial dysfunction, and the most severely affected hearts are unsuitable for transplantation. The cause of this acute heart failure is poorly understood. We investigated whether alterations in calcium-handling proteins, b-adrenoceptor density, or the inhibitory G protein Gia could account for this phenomenon in unused donor hearts ...