A novel approach to the synthesis of fully substituted pyrimidine derivatives armed with an oxy-functionalized acetate chain at the ring is described. The manifold uses amidines as the nitrogen source and activated skipped diynes as the electrophilic reactive partners in a coupled domino strategy. In the first domino reaction, two consecutive aza-Michael additions assemble the six-membered ring...

Low-power, compact, and highperformance NP dynamic CMOS circuits are presented in this paper assuming a 16 nm carbon nano tube transistor technology. The performances of two-stage pipeline 32-bit carry lookahead adders are evaluated based on HSPICE simulation with the following four different implementations: silicon MOSFET (Si-MOSFET) domino logic, Si-MOSFET NP dynamic CMOS, carbon nanotube MO...

Sharing data between widely distributed intrusion detection systems offers the possibility of significant improvements in speed and accuracy over isolated systems. In this paper, we describe and evaluate DOMINO (Distributed Overlay for Monitoring InterNet Outbreaks); an architecture for a distributed intrusion detection system that fosters collaboration among heterogeneous nodes organized as an...

Because domino logic design offers smaller area and faster delay than conventional CMOS design, it is very popular in the high-performance processor design. However, domino logic suffers from several design problems and one of the most notable ones is the chargesharing problem. In this paper, we describe a method to measure the sensitivity of the charge-sharing problem for each domino gate. In ...

Many protein interactions are mediated by small protein modules binding to short linear peptides. DOMINO (http://mint.bio.uniroma2.it/domino/) is an open-access database comprising more than 3900 annotated experiments describing interactions mediated by protein-interaction domains. DOMINO can be searched with a versatile search tool and the interaction networks can be visualized with a convenie...

Using growth diagrams, we define skew domino Schensted algorithm which is a domino analogue of “Robinson-Schensted algorithm for skew tableaux” due to Sagan and Stanley. The color-to-spin property of Shimozono and White is extended. As an application, we give a simple generating function for a weighted sum of skew domino tableaux whose special case is a generalization of Stanley’s sign-imbalanc...

In this paper computer program THERMOCALC, GIBBS and THERIAK-DOMINO are discussed and pseudosections are generated on some chemical data taken from the published literature from the Himalaya and Alps and also new chemical and EPMA data generated from the Garhwal Himalaya to demonstrate the capabilities of THERMOCALC and THERIAK-DOMINO. Usefulness and limitations of computed pseudosections (equi...

System structure and a 2GHz product application result are described for a domino synthesis capability that covers all aspects of domino design, from estimation to silicon-ready layout, with custom-class optimization. The described optimization flow, abstraction modes, and key cost factors deliver power-optimized, noise-correct domino performance on complex logic. Introduction Domino logic is e...