Total motile sperm count and DNA fragmentation Index are two parameters in analysis that have recently been used to determine the outcome of management cases male infertility. Motile Sperm Count is one values considered better than 2010 World Health Organization standard terms predictive value for success spontaneous ongoing pregnancy rate. High Fragmentation were associated with lower an incre...

The aim of this study was to evaluate the potential use of a DNA comet assay, DNA fragmentation fluorimetric assay and reactive oxygen species levels as potential biomarkers of genome conditions of dental pulp stem cells (DPSCs) isolated from dog canine teeth. Mesenchymal stem cells were isolated from the dental pulp collected from dog teeth. The results obtained suggest the ideal moment for cl...

Pulp samples of 50 healthy human teeth with indication for extraction were examined to evaluate the role of apoptosis in pulp elimination during physiological root resorption. Two groups were formed: a test group (n=30) composed of pulp samples of primary teeth with physiological root resorption and a control group (n=20) composed of pulp samples of permanent maxillary third molars. Morphologic...

OBJECTIVE To assess the effects of a selective serotonin reuptake inhibitor on semen parameters. DESIGN Prospective study. SETTING Academic medical center. PATIENT(S) Thirty-five healthy male volunteers, 18-65 years old. INTERVENTION(S) Paroxetine administration for 5 weeks. MAIN OUTCOME MEASURE(S) Serum hormone levels, semen analyses, percent sperm DNA fragmentation, and questionnair...

OBJECTIVE This study was carried out to investigate the correlations of the sperm DNA fragmentation index (DFI) with semen parameters and apoptosis, and to investigate the effects of density-gradient centrifugation (DGC) and magnetic-activated cell sorting (MACS) on reducing the proportion of sperm with DNA fragmentation and protamine deficiency. METHODS Semen analysis and a sperm DNA fragmen...

BACKGROUND In humans, sperm DNA fragmentation rates have been correlated with sperm viability rates. Reduced sperm viability is associated with high sperm DNA fragmentation, while conversely high sperm viability is associated with low rates of sperm DNA fragmentation. Both elevated DNA fragmentation rates and poor viability are correlated with impaired male fertility, with a DNA fragmentation r...

Background: Sperm that bypasses natural apoptosis may find their way into semen. In order to avoid the insemination of such sperm during an intracytoplasmic sperm injection (ICSI) treatment, novel sperm selection procedures such as the Zeta procedure have been implemented. Therefore, the aim of this study was to evaluate whether this procedure, in addition to reducing the number of immature or ...