We describe the clinical and pathologic observation of four patients with Porokeratosis of Mibelli. Allof them were women. They had four different forms of disease: Plaque type, functate form, Linear form and superficial disseminated form. In histologic features we observed a new change in basement membrane of epidermis in two patients. This change composed of Liquefaction degeneration of basal...

Porokeratoses represent a group of uncommon, acquired or hereditary dermatoses, due to a keratinization disorder whose origin is still unclear; they could be due to the expansion of a clone of abnormal epidermal keratinocytes. Several clinical forms exist, of which the most common is disseminated superficial actinic porokeratosis; other forms include Mibelli, disseminated superficial, linear, p...

BACKGROUND Disseminated superficial actinic porokeratosis (DSAP) is one clinical subtype of porokeratosis, a cutaneous disorder of keratinization. A variety of approaches may be used to treat DSAP. The ruby laser appears to be a promising option for DSAP treatment. Traditionally, the ruby laser is used to treat hair removal and lesions involving hyperpigmentation. Its use may be further applied...

Vol. 30, No. 2, 2018 249 Received December 12, 2016, Revised April 10, 2017, Accepted for publication May 6, 2017 Corresponding author: Mu-Hyoung Lee, Department of Dermatology, Kyung Hee University Medical Center, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea. Tel: 82-2-958-8512, Fax: 82-2-969-6538, E-mail: [email protected] This is an Open Access article distributed under the terms of t...

Sir, Disseminated porokeratosis palmaris and plantaris (DPPP), a subtype of porokeratosis Mibelli, is a rare autosomal dominant genodermatosis first described by Guss et al. in 1971 (1). An early review of the literature showed that 7% of 250 patients with porokeratosis subsequently developed skin tumours (2). Squamous cell carcinomas (SCC), Bowen’s disease (BD), and rarely, basal cell carcinom...