Superoxide dismutase is antioxidant enzyme responsible for the quenching of superoxide radicals which are released during the chemical reactions of the various metabolic pathways. It is a non-heme protein. Different iso-enzymes of superoxide dismutase are described. The mitochondrial enzyme is manganese dependent, cytoplasmic enzyme is copper-zinc dependent. These enzymes are evenly and ubiquit...

The activities of superoxide dismutase and glutathione peroxidase in the red cells of normal and acatalasemia bloods were compared. Superoxide dismutase activity in the red cells of Japanese acatalasemia blood was higher than in normal control, while glutathione peroxidase activity remained within normal limits. Cyanide sensitivity of superoxide dismutase in the red cells of acatalasemia blood ...

The superoxide dismutase (dismutase) which has already been found to be useful in detecting the role of O2 ain certain enzymic reactions has here been shown to be applicable to the study of nonenzymic reactions, as well. The aerobic oxidation of sulfite, which proceeds by a free radical chain mechanism, has been investigated with the aid of superoxide dismutase. The “spontaneous” oxidation of s...