Coexistence of ankylosing spondylitis with connective tissue diseases is uncommon. We describe here the coexistence of ankylosing spondylitis and systemic lupus erythematosus in a 35-year-old man. He presented with a 4-year history of pain in the hip joint and lower spine, and he later developed a malar rash and discoid rash. Immunological tests revealed that antinuclear antibody and double str...

Linear cutaneous lupus erythematosus (LCLE) is rare. The LCLE was proposed by Abe et al. [1] for discoid lupus erythematosus (DLE) with a linear configuration in 1988. It occurs mainly in children and young adults. Lesions appear as linear unilateral erythematous plaques following the Blaschko lines and are observed most frequently on the face, although the neck, trunk and extremities may also ...

1. Nelson WE, Vaughan III, VC, McKay, Jr., RJ and Behrman RE, editors. Textbook of pediatrics, Philadelphia, 1979, W B Saunders Company. 2. Rudolph AM, Barnett HL, and Einhorn AH, editors: Pediatrics, ed 16, New York, 1977, Appleton-CenturyCrofts. 3. Irgang S: Lupus erythematosus profundus. Report of an example with clinical resemblance to Darier-Roussy sarcoid, Arch Dermatol 42:97, 1940. 4. Fo...

A thirty-year-old patient presented with an erythematous papule on the left nostril evolving for ten months. clinical examination revealed infiltrated, erythematous, well-limited plaque a raised border, covered multiple open and closed comedones. On dermoscopy, there was background some fine telangiectasias horny plugs at follicular orifices. skin biopsy performed, revealing orthokeratotic hype...

A 35-year-old woman with discoid lupus erythematosus (DLE) was admitted at 11 weeks' gestation with a persistent fever. Laboratory studies revealed pancytopenia, elevated liver enzymes, and hyperferritinemia. Bone marrow aspiration confirmed the diagnosis of hemophagocytic syndrome (HPS). She had no findings of infection or active systemic lupus erythematosus. The administration of high-dose co...

Discoid lupus erythematosus (DLE), which is a cutaneous form of lupus erythematosus (LE), is generally refractory to a wide range of topical or systemic therapies. Although the main treatment option for DLE is topical steroids, it is often ineffective or likely to produce long-term side effects. New drugs, including tacrolimus and pimecrolimus, have been developed to overcome the adverse effect...

Cutaneous lupus erythematosus (CLE) encompasses a wide range of dermatologic manifestations, which may or may not be associated with the development of systemic disease. Cutaneous lupus is divided into several sub-types, including acute CLE (ACLE), sub-acute CLE (SCLE) and chronic CLE (CCLE). CCLE includes discoid lupus erythematosus (DLE), LE profundus (LEP), chilblain cutaneous lupus and lupu...

Previous studies have shown elevated IL-12 and -17 (7) and p40 subunit expression in patients with systemic lupus erythematosus (SLE) at levels correlating with disease severity (8). In theory, this overexpression of p40 could be a target for treatment in patients with CCLE. Two recent case reports have also reported marked improvement in skin lesions in a patient with subacute cutaneous lupus ...

The incidence of skin cancers is low in India when compared to the western world. Malignant transformation discoid lupus erythematosus (DLE) a rare entity. Most common site head and neck. Our case reported disseminated DLE with malignant squamous cell carcinoma (SCC) lesion over arm axillary node involvement. We proceeded wide local excision dissection.