Lupus erythematosus complex is an immune-mediated dermatological disease, mainly represented by the generalized and discoid forms. The last form described milder, as it limited to appearance of lesions, usually on face in mucocutaneous regions. Its pathophysiology considered multifactorial, however, continuous exposure ultraviolet radiation seems be very relevant trigger and/or worsen clinical ...

Rifat Yasmin, Ikramullah Khan, Anwar Ul Haque, Syed Afaq Ahmad Objective: To determine the frequency of sebaceous granulomas formation in discoid lupus erythematosus. Study Design: Retrospective observational study. Setting: Departments of Dermatology and Pathology, Pakistan Institute of Medical Sciences, Islamabad. Material and Methods: 100 cases of Discoid Lupus Erythematosus (DLE)spanning ov...

OBJECTIVE To determine the demographic data, clinical pattern and therapeutic outcome in patients with discoid lupus erythematosus (DLE). STUDY DESIGN Case series. PLACE AND DURATION OF STUDY The Department of Dermatology, Liaquat University of Medical and Health Sciences, Jamshoro, from January 2004 to December 2008. METHODOLOGY Patients of either gender aged above 18 years diagnosed wit...

In our previous experiments with linear strips of adhesive substrate, we found that elongated cultured fibroblasts preserve their length regardless of cell width and the number of cytoplasmic processes. This constancy of length was called 'length control'. In contrast to fibroblasts, single cultured epitheliocytes have nearly discoid shape on the plane substrata and have no length-controlling m...