Technical iodine was found to catalyze the condensation between 2-aminobenzohydrazide (1) and some aldehydes and ketones in absolute ethanol under mild conditions to afford hydrazone and quinazoline derivatives, respectively. Condensation of 1 with terephthalaldehyde (2) in 1 : 1 molar ratios afforded the hydrazone 3, while hydrazone 4 was formed on using a double molar ratio of 1. On the other...

Extensive kinetic studies were performed to investigate the mechanism of the reaction between 4-methoxybenzaldehyde 1, malononitrile 2, and dimedone 3 in the presence of fructose as a catalyst in a mixture of water and ethanol. The synthesis reaction of tetrahydrobenzo[b]pyran followed second-order kinetics. The partial orders with respect to 1, 2 were one and one, respectively. Temperature eff...

Abstract Study question Are S-sulfenylation and S-nitrosylation, two essential posttranslational modifications (PTMs), increased during sperm capacitation? Which proteins are subjected to S-sulfenylation? Summary answer S-nitrosylation increase capacitation. affects certain proteins, including A-kinase anchor protein 13, Fibrilline-1, Spermatogenesis-associated 7. What is known already There a ...

In the recent decades, heterocyclic compounds six membered ring occupied a great deals of attention due to its wide and varied applications in medical, pharmaceutical, agricultural industrial fields. Herein this work fused pyrimidine as active type mentioning above have been successfully prepared by using supreme green chemistry techniques represented solid phase one-pot muticomponent reaction ...

This study introduces a green and efficient method for preparation of biologically-active substituted 4H-pyrans using the one-pot three-component reaction of aromatic aldehydes, dimedone and malononitrile in the presence of cobalt oxide nanoparticles. Co3O4 nanoparticles were used as an efficient catalyst for the synthesis of polyhydroquinoline derivatives by the reaction ...

silica-bonded n-propyltriethylene-tetramine (sbnptt) was found as an efficient solid base for the synthesis of 2-amino-5-oxo-5,6,7,8-tetrahydro-4h-chromenes. chromene derivatives were obtained via the three-component condensation reaction of aromatic aldehydes, malononitrile, and dimedone at 80 oc under solvent-free conditions. the heterogeneous solid base showed much the same efficiency when u...

the efficient and environmentally friendly method for the one-pot synthesis of polyhydroquinolines has been developed in the presence of cuo nanoparticles. the multi-component reactions of aldehydes, dimedone, ethyl acetoacetate andammonium acetate were carried out under solvent-free conditions to afford some polyhydroquinoline derivatives. this method provides several advantages including high...