Geometric distortions of echo-planar images produced by the strong eddy currents present in the diffusion tensor imaging experiment are a major confound to the accurate quantification of diffusion coefficients, and measures of diffusion anisotropy based upon them. Here we investigate how the method of iterative cross-correlation (ICC) of baseline and diffusion-weighted images (DWIs) originally ...

Diffusion Tensor Imaging (DTI) is a relatively new imaging modality that has been extensively used to study diffusion processes in the brain and has applications ranging from diagnostic to surgical planning. However, DTI imaging systems are highly sensitive to noise, leading to reconstructed images with low SNR. Thus, there is a need for image denoising algorithms specifically designed to regul...

Introduction: High-angular resolution diffusion imaging (HARDI) is a powerful extension of MRI that maps the directional diffusion of water in the brain, based on applying diffusion-sensitized gradients in 30-100 or more different directions. In the Diffusion Tensor (DT) model, a tensor is fitted to the set of diffusion images, and maps of fiber integrity such as fractional or relative anisotro...

Major advances in medical imaging raised the need for adapted methods and softwares. The recent emergence of diffusion tensor MRI (DT-MRI) was challenging since data produced by this modality are not simple grey-value images but complex diffusion tensor fields. Tensors are symmetric, positive definite matrices and suffer from a lack of adapted theoretical tools to manipulate them. In this paper...

Registration or spatial normalization of diffusion tensor images plays an important role in many areas of human brain white matter research, such as analysis of Fraction Anisotropy (FA) or whiter matter tracts. More difficult than registration of scalar images, spatial normalization of tensor images requires two important parts: one is tensor interpolation, and the other is tensor reorientation...

In magnetic resonance diffusion tensor imaging (DTI), the direction and magnitude of diffusion of water molecules is characterized by a diffusion tensor. In the central nervous system, the highly organized fibre structure of white matter fibre tracts causes the diffusion to be anisotropic. From the DTI data, one can calculate a vector field representing the preferred direction of diffusion at e...