Introduction: Liver ischemia/reperfusion (IR) is a major clinical problem, which occurs during several conditions such as liver damage, trauma and transplantation. Recent studies indicate that IR-induced acute liver failure causes injuries of distant organs such as heart and lungs by systematic inflammatory responses. Therefore, in the present study, effects of hepatic IR induction were stud...

BACKGROUND Fibrillary glomerulonephritis is a rare cause of progressive renal dysfunction, often leading to the need for dialysis within a few years. The role of immunosuppressive treatment is still uncertain although this has been tried with variable success. CASE PRESENTATION A 56 year old woman with the antiphospholipid antibody syndrome (IgM anticardiolipin antibodies) was seen in the nep...

how to cite this article: afsharkhas l, tavasoli a. renal function in children with febrile convulsions.iran j child neurol. 2014 autumn;8(4):57-61. abstract objective febrile convulsions (fc) are the most frequent seizure disorder in children. some studies have detected serum electrolyte disturbances in patients with fc. this study determines serum electrolytes, renal function tests, and frequ...

BACKGROUND Pyeloplasty is a widely accepted treatment for ureteropelvic junction obstruction (UPJO). However, the renal function recoverability after pyeloplasty is still a matter of debate. Different parameters have been used to predict renal functional recoverability after corrective surgery, with conflicting results. OBJECTIVES In this study, renal biopsy was carried on a series of cases o...

Today, an increase in vancomycin dose has been proposed to ensure efficacy. However, the risk of nephrotoxicity will increase with the dose. This study was aimed at evaluating the dosage regimens of vancomycin in pediatric patients based on pharmacokinetics/pharmacodynamics (PK/PD) and to optimize dosage individualization. Population pharmacokinetics analysis was performed on 155 Chinese childr...

Scintigraphy with Tc-99m dimercaptosuccinic acid (DMSA) is considered a reference method for assessment of parenchymal lesions and estimation of differential kidney function. The aim of study was to evaluate Tc-99m mercaptoacetyltriglycine (MAG3) dynamic renal scintigraphy for the same purpose. 188 patients, submitted to both studies within three months, were divided in two groups. In the first...

background and objective: cystinosis is a rare inherited disease that leads to renal failure. fanconi syndrome is the major renal involvement in cystinosis patients. renal transplantation is the treatment of choice in cystinosis children with end-stage renal disease (esrd).  the study aimed to assess the outcome of renal transplantation in iranian children with cystinosis. methods: this retrosp...

Today, an increase in vancomycin dose has been proposed to ensure efficacy. However, the risk of nephrotoxicity will increase with the dose. This study was aimed at evaluating the dosage regimens of vancomycin in pediatric patients based on pharmacokinetics/pharmacodynamics (PK/PD) and to optimize dosage individualization. Population pharmacokinetics analysis was performed on 155 Chinese childr...

BACKGROUND High-grade blunt renal trauma has been treated by arterial embolization (AE). However, it is unknown whether AE preserves renal function, because conventional renal function tests reflect total renal function and not the function of the injured kidney alone. Dynamic scintigraphy can assess differential renal function. METHODS We performed AE in 17 patients with grade-4 blunt renal ...