Identifying latent structure in large data matrices is essential for exploring biological processes. Here, we consider recovering gene co-expression networks from gene expression data, where each network encodes relationships between genes that are locally co-regulated by shared biological mechanisms. To do this, we develop a Bayesian statistical model for biclustering to infer subsets of co-re...

K e y w o r d s N e u t r a l functional differential equation, Analytic semigroup, Mild solution, FaedoGalerkin approximation. 1. I N T R O D U C T I O N Let H be a separable Hilbert space and 0 < T, T < ec. For 0 < t < T, Ct := C([-~-, t]; H) be the Banach space of all continuous functions from l--T, t] into H endowed with the supremum norm, Ilullt := sup I lu(s) l l , u • Ct, (1.1) -r<_s<t w...

LTCC-based pressure sensors are promising candidates for wet-wet applications in which the effect of the surrounding media on the sensor’s characteristics is of key importance. The effect of humidity on the sensor’s stability can be a problem, particularly in the case of capacitive sensors. A differential mode of operation can be a good solution, but manufacturing the appropriate sensing capaci...

Identifying the genes that change their expressions between two conditions (such as normal versus cancer) is a crucial task that can help in understanding the causes of diseases. Differential networking has emerged as a powerful approach to detect the changes in network structures and to identify the differentially connected genes among two networks. However, existing differential network-based...

Integrated performance simulation of buildings and heating, ventilation and airconditioning (HVAC) systems can help reducing energy consumption and increasing occupant comfort. However, no single building performance simulation (BPS) tool o ers su cient capabilities and exibilities to analyze integrated building systems and to enable rapid prototyping of innovative building and system technolog...

As a consequence of falling relative demand for low skilled labor in the OECD, people with no or minor qualification experience a deterioration of their economic situation. While flexible labor markets have led to higher wage differentials in the USA, the major problem of most European countries is the high rate of unemployment of the low skilled. To integrate currently discussed determinants o...

Game theory is concerned with optimization problems involving several players with conicting interests. Di erential games are an interesting area inside this eld in which the problem is formulated by means of dynamical systems. In spite that the theoretical solution of di erential games is well known, faced with large-scale, complex systems, analytical or, even, numerical methods are not usuall...

The acetogen Clostridium thermoautotrophicum was cultivated under CO-dependent chemolithotrophic conditions. CO-dependent growth profiles and energetics indicated that supplemental CO2 was fundamental to efficient growth at the expense of CO. Overall product stoichiometry approximated 6.5CO----CH3CO2H + 3.5CO2 + 0.6 cell C + 0.5 unrecovered C. Initial CO/CO2 ratios of 2 to 4 yielded optimal dou...

The differential diagnosis of Cushing's syndrome requires careful multidisciplinary interaction with a number of specialities, co-ordinated through endocrine centres with good experience of this condition. It is essential that the diagnosis of Cushing's syndrome be fully established before differential diagnosis is attempted. The endocrinologist needs to be aware of the pitfalls and advantages ...