Two new brominated selinane sesquiterpenes, 1-bromoselin-4(14),11-diene (1) and 9-bromoselin-4(14),11-diene (2), one known cadinane sesquiterpene, cadalene (3), and four known selinane sesquiterpenes, alpha-selinene (4), beta-selinene (5), beta-dictyopterol (6), and cyperusol C (7), were isolated from a sample of marine brown alga Dictyopteris divaricata collected off the coast of Yantai (China...

In the title mol-ecule, C(15)H(18)O(2)S, the dimethyl-cyclo-hexa-diene unit is slightly non-planar, having a folded conformation with the two double-bond planes forming a dihedral angle of 3.9 (6)°. Methyl groups of the dimethyl-cyclo-hexa-diene ring tilt away from each other, forming inter-nal C-C-C(Me) angles approximately 11° greater than the exterior angles.

A facile synthesis of the side chain of loteprednol etabonate, namely, chloromethyl-17α-[(ethoxycarbonyl))oxy]-11β-hydro of loteprednol etabonate, viz., chloromethyl-17α-[(ethoxycarbonyl))oxy]-11xy-3-oxoandrosta-1,4-diene-17β-carboxylate--an ocular soft corticosteroid, has been described starting from a 20-oxopregnane, namely, 3β-acetoxy-pregn-5(6),16(17)-diene-20-one (16-dehydropregnenolone ac...

The hindered diene 1 reacts with 3-methylcyclohexenone 6 catalyzed by triflimide to produce the Mukaiyama Michael product 7 (low-temperature quenching) or the [4+2] cycloadduct 8 (quenching at 0 degrees C). Reaction of the hindered diene 23 with 2-methylcyclohexenone 12 with 5:1 AlBr3:AlMe3 afforded a 71% yield of a 1.9:1 mixture of two cycloadducts. Hydrolysis of the major isomer gave the dion...

A reaction between [(COD)IrCl]2 (COD is cyclo-octa-1,5-diene), HCl and indene failed to provide the hoped for chlorido-indenyliridium dimer, but instead produced the title compound, [IrCl3(CH3CN)(C8H12)], which is an octa-hedral complex of iridium(III) with a chelating cyclo-octa-1,5-diene ligand, three chloride ligands in a fac arrangement, and one aceto-nitrile ligand. Attempts to devise a ra...

The present study is aimed to examine and compare the storage stability of seed kils extracted form red pepper (Capsicum annuum L.) waste by green techniques (cold pressing, ethanol solvent, ultrasound-assisted solvent extraction). In accordance with this purpose, oil samples were stored for a period 6 weeks at 60°C under accelerated conditions analyzed weekly intervals peroxide, conjugated die...

Circular dichroism (CD) data are reported of a series of 9,10stereoisomeric steroidal 5,7-dienes. In general the effects in the longest wavelength transition (270-280 nm) are large (Mm" 10---30) and consignate with respect to the diene helicity rule. The magnitude of the CD appears to vary markedly with the substituent at C-3 and at C-17, and with solvent. In the case of the 9a,10p-H dienes, va...

Progesteronereceptorsof humantumorsof breast and gynecologicaloriginwere assayed with [6,7-3H]-17,21-di methyb-19-norpregna-4,9-diene-3,20-dione or [1,2,6,7-3H]progesterone plus a 100-fold excess of cortisol by the charcoal extraction method. Whereas both ligands gave concordantlevels of bindingfor the high-capacitysam pies,highernonspecific bindingof I 7,21-dimethyl-1 9-nor pregna-4,9-diene-3,...

Olefin metathesis reactions with 3E-1,3-dienes using Z-selective cyclometalated ruthenium benzylidene catalysts are described. In particular, a procedure for employing 3E-1,3-dienes in Z-selective homodimerization and cross-metathesis with terminal alkenes is detailed. The reaction takes advantage of the pronounced chemoselectivity of a recently reported ruthenium-based catalyst containing a cy...