BACKGROUND The optimum blood pressure target in hypertension remains debated, especially in coronary artery disease, given concerns for reduced myocardial perfusion if diastolic blood pressure is too low. We aimed to study the association between achieved blood pressure and cardiovascular outcomes in patients with coronary artery disease and hypertension. METHODS We analysed data from 22 672 ...

Ten patients with valvular pulmonic stenosis were studied by simultaneous external phonocardiograms and intracardiac pressure recordings during successive respiratory cycles to examine the mechanism of the respiratory variation in the ejection click. Selective cineangiograms were perforned in four. During inspiration right ventricular end-diastolic pressure (RVEDP) exceeded the pressure in the ...

The phenomenon of negative right ventricular diastolic pressure immediately after operation for relief of isolated pulmonary valve stenosis was investigated in 11 patients. Pressures in the right ventricle and pulmonary artery were measured with a catheter tip micromanometer. One patient had a negative right ventricular diastolic pressure before operation. At the end of operation right ventricu...

Continuous-wave Doppler echocardiography was used to estimate pulmonary artery pressures by measuring pulmonary regurgitant flow velocity in 21 patients with pulmonary hypertension (mean pulmonary artery pressure greater than or equal to 20 mm Hg) and 24 patients without pulmonary hypertension. The pulmonary regurgitant flow velocity patterns, characterized by a rapid rise in flow velocity imme...

background: the obesity and hypertension are the major risk factors of several life threatening diseases. the present study was aimed to investigate the relation between body mass index (bmi) the validated index of adiposity and different aspect of blood pressure (bp). methods: systolic and diastolic blood pressures and also weight and height of 7 to 18 years old children and adolescent col­lec...

OBJECTIVE Calcium antagonists are the only oral vasodilators shown to influence mortality in primary pulmonary hypertension, but the high doses required are often poorly tolerated. Amlodipine is a novel, relatively well tolerated, calcium antagonist. It has not been previously tested in humans with pulmonary hypertension. DESIGN Calcium antagonists are claimed to be of benefit in the 20-30% o...

introduction: obesity is an independent risk factor in developing cvd, type ii diabetes, and gall bladder disease, different types of cancers, osteoarthritis and mortality. weight gain during adult life, especially during the third and fourth decades, is associated with increased blood pressure. methods: random samples of nearly 1493 men and women aged between 16 to 85 years old were selected f...

conclusions based on the results of this study, we suggest the use of a novel “time from the beginning of isovolumetric contraction to the peak of the s wave” (ttp) parameter in the tdi of the base of the rv free wall to predict ph with acceptable accuracy in comparison with rhc. results in our study, the ttp showed a significant inverse relationship with the pap. based on our results, a ttp of...

The practicality of vigorous lowering of systolic pressure in diabetes to 130 mmHg remains uncertain. Baseline blood pressure data from several recent trials indicate that, in diabetic subjects, there is nearly a fourfold excess in systolic pressure (the difference between baseline pressure and target pressure) over diastolic pressure with respect to the recommended systolic/diastolic target pr...