In this feature article we discuss the particular relevance of glycans as components or targets of functionalized nanoparticles (NPs) for potential applications in personalized medicine but we will not enter into descriptions for their preparation. For a more general view covering the preparation and applications of glyconanomaterials the reader is referred to a number of recent reviews. The co...

The laboratory medicine is advancing towards the use of molecular techniques and molecular diagnostics for the detection of leukemia, genetic disorders, preimplantation screenings, pharmacogenomics, infectious diseases, and cancers. Molecular diagnostics dates back to 1980s but now has grown exponentially. The field has a wide range of applications including identifying individuals at risk of d...

I discuss diagnostic methods for discriminant analysis. The equivalence with linear regression is noted and regression diagnostics are considered. The leverage is a function of the linear discriminant function and the Mahalanobis distance of the observation from the group mean. The distribution of this distance is approximately chi-square with degrees of freedom equal to the number of variables...

Methods for detecting influential observations for the Weibull model fit to censored data are discussed. These methods include: one-step deletion diagnostics, influence functions and curvature diagnostics. Results indicate that the curvature diagnostics may be helpful in detecting masking.

This article describes the software and underlined decision support models for the immunophenotype diagnostics of leukosis (leukemia) and lymphomas adjusted for the marker or human leukocyte antigen (CD-antigen) coexpressions. Using the model knowledge base, the decision inference algorithm allows computing the degree of manifestation of the disease subtypes for the input immunophenotype featur...

Yoon (2008, 2009) claimed that there are two distinct Subjects in Multiple Subject Constructions (MSCs) in Korean. The crux of his argument hangs on reinterpreting the traditionally proposed subject diagnostics as distinguishing between the Grammatical Subject (GS) and the Major Subject (MS) in MSCs. The claimed diagnostics for GS and MS were examined experimentally in MSCs and corresponding Si...

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People can usually sense troubles in a car from noises, vibrations, or smells. An experienced driver can even tell where the problem is. We call this kind of skill ‘Ambient Diagnostics’. Ambient Diagnostics is an emerging field that is aimed at detecting abnormities from seemly disconnected ambient data that we take for granted. For example, the human body is a rich ambient data source: tempera...

Statistical diagnostic and correction of a chemistry-transport model for the prediction of total column ozone S. Guillas, G. C. Tiao, D. J. Wuebbles, and A. Zubrow School of Mathematics, Georgia Institute of Technology, Atlanta, Georgia, USA Graduate School of Business, University of Chicago, Chicago, Illinois, USA Department of Atmospheric Sciences, University of Illinois, Urbana, Illinois, US...

Various methods exist to detect an astrovirus infection. Current methods include electron microscopy (EM), cell culture, immunoassays, polymerase chain reaction (PCR) and various other molecular approaches that can be applied in the context of diagnostic or in surveillance studies. With the advent of metagenomics, novel human astrovirus (HAstV) strains have been found in immunocompromised indiv...