This study was performed to assess the effect of chlorpropamide therapy on the fibrinolytic activity of blood of maturity onset diabetics. Normal controls were also studied and the results compared with diabetics. Diabetics were found to have deficient fibrinolytic activity compared with non-diabetics but chlorpropamide did not appear significantly to affect this deficiency either in males or f...

To investigate the quality of glycaemic control that is achievable in diabetic patients with persistent proteinuria and asymptomatic but declining renal function three matched groups of patients were studied. The first comprised diabetics with proteinuria receiving continuous subcutaneous insulin infusion; the second, diabetics without proteinuria receiving continuous subcutaneous insulin infus...

BACKGROUND Neutrophil gelatinase-associated lipocalin (NGAL), an acute phase protein released by neutrophils, has been described as biomarker of inflammatory states. Type 2 diabetes mellitus (T2DM) is characterized by increased inflammation and an elevated risk for embolization of carotid artery stenosis (CAS). We aimed to explore the role of NGAL systemically and in plaques of diabetics underg...

Cadmium (Cd) has recently emerged as a major concern not only in environmental toxicology but also in metabolic diseases such as diabetes mellitus and its complications. Conflicting data aside, these studies have not been examined in a clinical population undergoing management as well as possible modulation by the prominent metabolic antagonist of Cd such as zinc (Zn). This study examined the r...

background: the potential role of lipoprotein (a) changes and also inflammation in coronary artery disease (cad) have rendered these processes one of the most interesting objects of study in patients affected by type 2 diabetes mellitus. the aim of the current study was to evaluate lipoprotein (a) and other lipid profiles and also c-reactive protein (crp) as the predictors of cardiovascular dis...

The objective was to identify whether diabetics have a higher incidence of sensorineural hearing loss than general population and examine its duration and control on severity of hearing loss. Materials: In one year prospective study, 102 Type II diabetic patients and 118 nondiabetic patients of age sex matched were tested on audiometric measures, including pure-tone thresholds. Pure tone averag...

INTRODUCTION Diabetes may affect the human body's systems and organs, including the eye. Diabetic retinopathy is the 5th leading cause of blindness globally. Diabetic subjects demonstrated dry eye symptoms that were also supported by the low values of the clinical tests. PURPOSE This study aimed to compare the dry eye symptoms and signs between diabetics and non-diabetics and tear functions b...

Objectives: Diabetes is a well-established risk factor for cardiovascular disease, and diabetics have a threefold increase in risk of death from cardiovascular disease compared to non-diabetics. Following coronary artery bypass grafting, tight glycemic control improves short-term outcomes, however limited data exist for long-term outcomes. Here we examine these outcomes in diabetics using aggre...