background: diabetes mellitus has a variety of structural and functional effects on the male reproductive system. diabetes results in reduced sperm parameters and libido. the present study aims to investigate the effects of royal jelly (rj) on reproductive parameters of testosterone and malondialdehyde (mda) production in diabetic rats. materials and methods: this experimental study was conduct...

conclusions therefore, our results suggest that although administration of 300 mg/kg of calendula officinalis extract showed salutary effects on anti-oxidant profile, yet its protective effects on anti-diabetic and regenerative properties on nephropathy were ambiguous and require more investigations. background chronic hyperglycemia leads to microvascular and macrovascular complications such as...

background: the relationship between the high activity of aldose reductase (ar) and diabetic cataract formation has been previously investigated. the purpose of the present study was to determine the preventing effect of melatonin on streptozotocin (stz)-induced diabetic cataract in rats. methods: 34 adult healthy male sprague-dawely rats were divided into four groups. diabetic control and diab...

aldose reductase is a critical enzyme in the polyol pathway that plays an important role in diabetes mellitus. inhibition of the activity of this enzyme can prevent cataract in diabetic patients’lenses. in this study the inhibitory effect of two flavonoids, quercetin and naringin, in the activity of aldose reductase in streptozotocin-induced diabetic and healthy rats were investigated. thirty m...

barley ( hordeum vulgare l.) is the world’s fourth most important cereal crop after wheat, rice and maize. it is readily available with reasonable cost, and has the highest amount of dietary fiber among the cereals which may be beneficial for metabolic syndrome. in the present study, the effect of hydroalcoholic extract of barley seeds and a protein enriched fraction on blood glucose of normal ...

objectives due to the known anti-oxidant and anti-diabetic effects of origanum majorana (om), this study was conducted to survey its effects on oxidative stress and histopathology of renal tissue among diabetic rats. materials and methods in this experimental investigation, 32 male rats, weighing 200 - 250 g, were divided into four groups: 1: control, 2: control receiving treatment with om, 3: ...

Objective: Crocinisa saffron constituent with a potent anti-oxidant activity. The present study investigated the effects of crocin and insulin treatments (alone or in combination) on cardiac function and pathology in diabetic rats. Materials and Methods: Diabetes was induced by intraperitoneal (i.p.) injection of streptozotocin (STZ, 50 mg/kg). Thereafter, crocin (5, 10 and 20 mg/kg, i.p.), sub...

background: diabetes mellitus in some clinical cases is accompanied with hyperalgesia. in this study, we evaluated the possible beneficial effect of chronic pelargonidin (pg) treatment on hyperalgesia in streptozotocin (stz)-diabetic neuropathic rat. methods: male wistar rats (n = 56) were divided into seven groups, i.e. control, diabetic, pg-treated control, pg (single- and multiple-dose)-trea...

protein amyloid beta (a?), as the pathologic hallmark of alzheimer disease (ad), increases in the brain of diabetic patients. the aim of this study was to investigate the effect of 6 weeks of voluntary wheel running combined with allium paradoxum extract on cortex amyloid beta (a?1-42) levels in diabetic rats induced with alloxan. for this purpose, 42 male wistar rats (weight 185+1 gr, 8 weeks ...

calendula officinalis (family compositae) flowers are recognized as safe substance for food use by food and drug administration. present study was aimed to determine the modulatory effect of floral extracts of c. officinalis administrations on mean blood glucose (mbg), per cent glycosylated hemoglobin (hba1c), lipid profile [(total cholesterol (tc), triglycerides (tg), low and high density lipo...