نتایج جستجو برای: diabetic cardiomyopathies

تعداد نتایج: 138987  

Journal: :Indian journal of biochemistry & biophysics 2014
Paramjit S Tappia Naranjan S Dhalla

Although diabetic cardiomyopathy is associated with heart dysfunction and disturbance in cardiac sarcolemmal membrane phospholipid composition, the role of the different phospholipases and their related signaling mechanisms to altered function of the heart in diabetes is not completely understood. Thus, understanding the pathophysiology of cardiovascular abnormalities in diabetes, as well as id...

2015
Haihan Liao Nan Zhang Ning Zhang Zhenguo Ma Zheng Yang Qizhu Tang Wei Zhang Xinjun Lei

OBJECTIVES Previous study has demonstrated that oleanolic acid (OA) possessing the anti-inflammatory and antioxidant properties, blunted high glucose induced diabetic cardiomyopathy, and ameliorated experimental autoimmune myocarditis in mice. However, little is known about its effects on pressure overload induced cardiac remodeling. Herein, we investigated the effect of OA on cardiac remodelin...

Journal: :The Turkish journal of pediatrics 2015
Zeynelabidin Öztürk E Nazlı Gönç Leman Akcan Selman Kesici İlker Ertuğrul Benan Bayrakçı

Heart transplantation indications in pediatric population include congenital heart diseases, cardiomyopathies and retransplants. Cardiomyopathy is the primary indication for 11 to 17 years of age. The surveillance after transplantation is a very important issue because of both the rejection risk and the adverse effects due to medications after transplantation. Immunosuppressive agents that are ...

Journal: :Cell metabolism 2010
Ryan T Birse Joan Choi Kathryn Reardon Jessica Rodriguez Suzanne Graham Soda Diop Karen Ocorr Rolf Bodmer Sean Oldham

High-fat-diet (HFD)-induced obesity is a major contributor to diabetes and cardiovascular disease, but the underlying genetic mechanisms are poorly understood. Here, we use Drosophila to test the hypothesis that HFD-induced obesity and associated cardiac complications have early evolutionary origins involving nutrient-sensing signal transduction pathways. We find that HFD-fed flies exhibit incr...

Journal: :European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2006
Antonio Pelliccia Domenico Corrado Hans Halvor Bjørnstad Nicole Panhuyzen-Goedkoop Axel Urhausen Francois Carre Aris Anastasakis Luc Vanhees Eloisa Arbustini Silvia Priori

Several relatively uncommon, but important cardiovascular diseases are associated with increased risk for acute cardiac events during exercise (including sudden death), such as hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), arrhythmogenic right ventricular cardiomyopathy (ARVC) and myo-pericarditis. Practising cardiologists are frequently asked to advise on exercise programmes...

2011
Vladislav Volarevic Nebojsa Arsenijevic Miodrag L Lukic Miodrag Stojkovic

Mesenchymal stem cells (MSCs) are multipotent, self-renewing cells that can be found in almost all postnatal organs and tissues. The main functional characteristics of MSCs are their immunomodulatory ability, capacity for self-renewal, and differentiation into mesodermal tissues. The ability of MSCs to differentiate into several cell types, including muscle, brain, vascular, skin, cartilage, an...

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