The reaction of [(CO)5Cr(THF)] with propynethioic acid amides, R–C≡C–C(=S)NMe2 (R = H, SiMe3), yields the thioamide complexes [(CO)5Cr–S=C(NMe2)C≡C–H] (1a) and [(CO)5Cr– S=C(NMe2)C≡C–SiMe3] (1b). Treatment of solutions of 1a or 1b with methyllithium generates, via deprotonation or desilylation, the lithium salt Li[(CO)5Cr–S=C(NMe2)C≡C] (2). On filtration over silica, 2 is readily reprotonated. ...

A new generation of organophosphate (OP) scavengers was obtained by synthesis of β-cyclodextrin-oxime derivatives 8-12. Selective monosubstitution of β-cyclodextrin was the main difficulty in order to access these compounds, because reaction onto the oligosaccharide was closely related to the nature of the incoming group. For this purpose, non-conventional activation conditions were also evalua...

In many areas of science and technology, patterned films and surfaces play a key role in engineering and development of advanced materials. Here, we present a versatile toolbox that provides an easy patterning method for cellulose thin films by means of photolithography and enzymatic digestion. A patterned UV-illumination of trimethylsilyl cellulose thin films containing small amounts of a phot...

A convenient two-step, one-pot synthesis of oligo(arylene–ethynylene) (OAE) type molecular wires in yields up to 70% via situ desilylation protected bis(alkynes) Me3SiC?CArC?CSiMe3 (Ar = 2,5-thienyl, 1,4-naphthylene, 9,10-anthrylene) and subsequent Sonogashira cross-coupling with S-(4-iodophenyl) ethanethiolate, 4-iodothioanisole, or 5-bromo-3,3-dimethyl-2,3-dihydrobenzo[b]thiophene is describe...

Pd-catalyzed carboxylic acid guided regioselective alkynylation of cage B(4)–H bonds in o-carboranes has been achieved for the first time using two different catalytic systems. In the presence of 5 mol% Pd(OAc)2 and 3 equiv. of AgOAc, the reaction of 1-COOH-2-R-C2B10H10 with R3SiC^CBr in ClCH2CH2Cl gives 4(R3SiC^C)-2-R -o-C2B10H10 in moderate to high yields. This reaction is compatible with alk...

Herein we describe an electroactive substrate that was designed to turn on the migration of mammalian cells. The migration of cells is important in many developmental and disease processes that are temporally regulated.[1] Mechanistic studies of cell migrationÐwhich depend on specific interactions of cell-surface receptors with ligands of the extracellular matrix[2]Ðare complicated by the large...