نتایج جستجو برای: dermcidin

تعداد نتایج: 87  

2014
Yan Xu Jianhui Xie Yu Cao Huaigu Zhou Yuan Ping Liankang Chen Lihua Gu Wei Hu Gang Bi Jianye Ge Xin Chen Ziqin Zhao

The identification of human body fluids or tissues through mRNA-based profiling is very useful for forensic investigations. Previous studies have shown mRNA biomarkers are effective to identify the origin of biological samples. In this study, we selected 16 tissue specific biomarkers to evaluate their specificities and sensitivities for human body fluids and tissues identification, including po...

Journal: :Acta dermato-venereologica 2015
Toshiaki Nakano Takashi Yoshino Takao Fujimura Satoru Arai Akira Mukuno Naoya Sato Kensei Katsuoka

Dermcidin (DCD), an antimicrobial peptide with a broad spectrum of activity against bacteria such as Propionibacterum acnes, is expressed constitutively in sweat in the absence of stimulation due to injury or inflammation. The aim of this study was to determine the relationship between DCD expression and acne vulgaris associated with P. acnes. The antimicrobial activity of recombinant full-leng...

Journal: :Forensic science international 2013
Annemieke van Dam Maurice C G Aalders Kevin van de Braak Huub J J Hardy Ton G van Leeuwen Saskia A G Lambrechts

A fingermark contains important forensic information of the donor, not only in its ridge pattern, but also in the chemical composition of its secretion. Detection and identification of these secretions can be done by immunolabeling. In this study, we describe for the first time a reproducible immunolabeling method that allows the simultaneous detection of multiple components of interest. This m...

2014
Masamoto Murakami Takaaki Kaneko Teruaki Nakatsuji Kenji Kameda Hidenori Okazaki Xiuju Dai Yasushi Hanakawa Mikiko Tohyama Akemi Ishida-Yamamoto Koji Sayama Paul Proost

"Pustulosis palmaris et plantaris", or palmoplantar pustulosis (PPP), is a chronic pustular dermatitis characterized by intraepidermal palmoplantar pustules. Although early stage vesicles (preceding the pustular phase) formed in the acrosyringium contain the antimicrobial peptides cathelicidin (hCAP-18/LL-37) and dermcidin, the details of hCAP-18/LL-37 expression in such vesicles remain unclear...

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