The use of solid dispersion techniques to modify physicochemical properties and improve solubility and dissolution rate may result in alteration to electrostatic properties of particles. Particle triboelectrification plays an important part in powder processing, affecting end product quality due to particle deposition and powder loss. This study investigates the use of glucosamine hydrochloride...

The lung dose and deposition patterns of drug delivered by dry powder inhaler are not known. The effects of inhaling 400 micrograms salbutamol delivered by dry powder inhaler (two 200 micrograms salbutamol Rotacaps), by pressurised metered dose inhaler, and by Acorn nebuliser were studied in nine subjects with chronic stable asthma. Technetium-99m labelled Teflon particles were mixed with micro...

Nanobiomaterials play an important role in nanobiotechnology and have made a great contribution to biomedical research and healthcare. Recent progress in nanobiomaterials has increased demand for multidisciplinary approaches from physical, biological and engineering sciences. Solid freeform fabrication (SFF) technologies are based on layer-by-layer deposition of materials which bring about new ...

In this work the steady-state flow in a commercial dry powder inhaler device, DPI (i.e., Turbuhaler) is described using computational fluid dynamics. The Navier-Stokes equations are solved using commercial CFD software considering different flow models, i.e., laminar, k-ε, k-ε RNG, and k-ω SST as well as large Eddy simulation. Particle motion and deposition are described using a Eulerian-fluid/...

Thin titanium dioxide (TiO2) films were studied as ion emitters for the laser-induced electron transfer desorption/ionization (LETDI) of metal complexes with organic reagents. The TiO2 films (350 nm thick) were deposited on the silicon substrates by e-beam evaporation of TiO2 powder. Copper complex with phthalocyanine, rhenium complex with thiocarbanilide and platinum complex with 8-quinolineth...

T h e h u m a n leukocyte ant igen (HLA) class II molecules are cell-surface glycoproteins involved in the regulat ion of i m m u n e responses. Allelic variation at the HLA class lI loci is an important consideration in major areas of medicine and biology. For instance, detailed knowledge of the allelic constitution at class lI loci is required for match ing of suitable donors and recipients f...

Li5FeO4/carbon nanotube (LFO/CNT) composites composed of sub-micron sized LFO and a nanocarbon with high electrical conductivity were successfully synthesized for the use as lithium ion predoping source in lithium ion cells. The phase of LFO in the composite was found to be very sensitive to the synthesis conditions, such as the heat treatment temperature, type of lithium salt, and physical sta...

Photovoltaic solar energy is a renewable form of electricity obtained directly from solar radiation using a semiconductor device called a photovoltaic cell. This article aims to map and identify the main characters and the evolution of the technological challenges presented by the technologies involving photovoltaic solar energy by monitoring patent documents filed between 2003 and 2011. Making...

A colloidal powder was prepared by fixing polyaniline (PANI, conducting polymer), poly(vinyl alcohol) (PVA, surfactant stabilizer) and a suitable dopant anion to silica-gel powder. This hydrophilic composite colloidal particle incorporates anions with the protonation of PANI in an acidic solution. The anion can be exchanged with other anions when the colloid is immersed in an acidic solution. T...