Hypocalcemic vitamin D (D)-depleted rats were supplemented with calcium or 1,25(OH)2D3, and the metabolism of D3 to 25(OH)D3 was studied. Infusion with 7 or 65 pmol 1,25(OH)2D3. 24 h-' led to normal or slight hypercalcemia associated with physiological and supraphysiological plasma concentrations of the hormone while calcium supplementation normalized plasma calcium despite 1,25(OH)2D3 concentr...

conclusions our data showed that inhalation of diazinon during pregnancy increased the hepatocyte area and hepatocyte apoptosis while it decreased the sinusoid area of the fetal liver. materials and methods twenty-five pregnant balb/c mice (25 - 30 gr) were divided into five equal groups in the animal lab of baqiyatallah university of medical sciences, tehran, iran. the normal group was without...

such aabiotic stresses like water stress are some of the most important threats to the production of agricultural crops. it is almost very rare to find a place with no stress where plants can reach their potential yield. a water stress of 17 percent decrease yield, due to its effect upon fruit setting is notable. therefore, a study was conducted in bushehr agricultural research center (located ...

background: fetal heart rate (fhr) extracted from abdominal electrocardiogram (ecg) is a powerful non-invasive method in appropriately assessing the fetus well-being during pregnancy. despite significant advances in the field of electrocardiography, the analysis of fetal ecg (fecg) signal is considered a challenging issue which is mainly due to low signal to noise ratio (snr) of fecg. objective...

AB STRA CT In order to assess the renal tubular site(s) at which sodium reabsorption is enhanced in chronic sodium-depletion, seven normal dogs, six saltdepleted dogs, and three normal dogs receiving aldosterone were studied during a steady-state water diuresis under Pentothal anesthesia and during progressive hypotonic saline diuresis. For both maintenance of the water diuresis and progressive...

Definition: Leucocyte-depleted blood components must contain < 5 × 10 leucocytes per unit (red cells) or adult therapeutic dose (platelets). Practical aspects: To achieve residual leucocyte counts of < 5 × 10, leucocyte-depletion should be carried out under controlled conditions, ideally within 48 h from the collection of the donor unit. The preparation of leucocyte-depleted blood components sh...

Extended (histone H1-depleted), 11-nm-thick chromatin fibers and condensed 25- to 35-nm-thick chromatin fibers, representing the first and second level of DNA folding in chromatin, respectively, as well as nucleosome core particles, were isolated from fetal rat brain cells and briefly exposed to N-ethyl-N-nitrosourea (EtNU) in vitro. The O6-ethyl-2'-deoxyguanosine (O6-EtdGuo):2'-deoxyguanosine ...

PURPOSE Studies implicate activation of complement among the processes involved in the pathogenesis of age-related macular degeneration (AMD). Questions pertain to the trigger(s) responsible for the complement-associated events. The authors previously reported that photooxidation products of A2E can activate complement. Here they have further explored these events. METHODS In vitro assays usi...

The effects, in vivo, of epinephrine, glucagon, and dibutyryl cyclic adenosine 3',5'-monophosphate (cyclic AMP) on the glycogen content of rat heart and liver and, in vitro, upon adenylate cyclase activity in homogenates of rat heart and liver were determined during the latter third of gestation and the neonatal period. Hepatic glycogen was depleted by epinephrine, glucagon, and dibutyryl cycli...