The stiffness of fracture fixation devices together with musculoskeletal loading defines the mechanical environment within a long bone fracture, and can be quantified by the interfragmentary movement. In vivo results suggested that this can have acceleratory or inhibitory influences, depending on direction and magnitude of motion, indicating that some complications in fracture treatment could b...

It is now well established that the voltage-sensing S4 segment in voltage-dependent ion channels undergoes a conformational change in response to varying membrane potential. However, the magnitude of the movement of S4 relative to the membrane and the rest of the protein remains controversial. Here, by using histidine scanning mutagenesis in the Shaker K channel, we identified mutants I241H (S1...

Paraxial Protocadherin (PAPC) encodes a transmembrane protein expressed initially in Spemann's organizer and then in paraxial mesoderm. Together with another member of the protocadherin family, Axial Protocadherin (AXPC), it subdivides gastrulating mesoderm into paraxial and axial domains. PAPC has potent homotypic cell adhesion activity in cell dissociation and reaggregation assays. Gain- and ...

A crucial attribute in movement encoding is an adequate balance between suppression of unwanted muscles and activation of required ones. We studied movement encoding across the primary motor cortex (M1) and supplementary motor area (SMA) by inspecting the positive and negative blood oxygenation level-dependent (BOLD) signals in these regions. Using periodic and event-related experiments incorpo...

Axial analysis is one of the fundamental components of space syntax. The space syntax community has suggested that it picks up qualities of configurational relationships between spaces not illuminated by other representations. However, critics have questioned the absolute necessity of axial lines to space syntax, as well as the exact definition of axial lines. Why not another representation? In...

In this paper, the lift-law method was applied to design the axial flow pump. Based on Reynolds time-averaged N-S equations and standard k turbulent model, three-dimensional air-water bubbly flow in an axial flow pump impeller was simulated. Under the condition of bubble void fraction of 5%, pressure and void fraction distributions were respectively obtained, movement of bubbles in the impeller...

occurance of social movements in egypt and other countries in the middle east and north africa, and their demonstrative impacts lead to attentions of analysts. in this article by different approach, the authors try to explain the chractristics and the nature of late social movement in egypt and breakdown of mubarak government in the framework of late theories of social movement and john fouran ...

Neck involvement in cases of rheumatoid arthritis is extremely common, and the radiological features have been investigated by several authors, particularly Martel (1961, 1964), Bland, Davis, London, Van Buskirk, and Duarte(1963), Serre, Simon, Janicot, and Levy (1964) and Conlon, Isdale, and Rose (1966). The features most characteristic are atlanto-axial subluxation, serial subluxation, and di...

a variety of nervous system components such as medulla, pons, midbrain, cerebellum, basal ganglia, parietal, frontal and occipital lobes have role in eye movement desensitization and reprocessing (emdr) processes. the eye movement is done simultaneously for attracting client's attention to an external stimulus while concentrating on a certain internal subject. eye movement guided by therap...