In a headwater catchment in the Oregon Coast Range, we find that solid-phase mass losses due to chemical weathering are equivalent in the bedrock and the soil. However, the long-term rate of mass loss per unit volume of parent rock is greater in the soil than in the rock. We attribute this finding to the effects of biotic processes in the soil and to hydrologic conditions that maximize contact ...

BACKGROUND Nitric oxide (NO), in addition to its potent vasorelaxant properties, may participate in growth regulation of cultured smooth muscle cells. It was recently demonstrated that in vivo endothelial injury induces the production of NO from L-arginine in the arterial wall. METHODS AND RESULTS We studied the effects of long-term administration of L-arginine, the precursor of NO, on neoint...

We use a novel, microfluidics-based technique to deconstruct the classical wound healing scratch assay, decoupling the contribution of free space and cell damage on the migratory dynamics of an epithelial sheet. This method utilizes multiple laminar flows to selectively cleave cells enzymatically, and allows us to present a 'damage free' denudation. We therefore isolate the influence of free sp...

We thank Warrick et al. (2014) for the Comment on our recent synthesis of 10Be-derived denudation rates (Willenbring et al., 2013), in which we suggested that gently sloping areas, representing ∼90% of the Earth’s land surface, have sufficiently high rates of denudation to produce a majority of mass fluxes to the world’s ocean. First, Warrick et al. take issue with labeling our global cosmogeni...

Denudation is one of the main processes that shapes landscapes. Because temperature, precipitation and glacial extents are key factors involved in denudation, climatic fluctuations thought to exert a strong control on this parameter over geological timescales. However, direct impacts variations denudation remain controversial, particularly those involving Quaternary cycles mountain environments...