Tooth agenesis denotes a condition where teeth are missing due to a developmental failure. According to severity, this malformation can be subdivided into hypodontia, oligodontia and anodontia. With a frequency of 20–30%, tooth agenesis is the most prevalent dental dysplasia, but not all teeth are equally affected. Familial occurrence and concordance in twins indicate potential genetic causes. ...

This case of a female patient, 14 yr old with association of the two anomalies, which we came across with in 2014, is rarely met in the specialty practice. The impacted canines are part of the group of dental anomalies of position, while the agenesis is part of the group of dental number anomalies. The orthodontic treatment in the two arches has to be differentiated, the therapeutic objectives ...

BACKGROUND The aim of this study was to describe the pattern of inheritance and the clinical features in a large family with Waardenburg syndrome type I (WS1), detailing the dental abnormalities and screening for PAX3 mutations. MATERIAL AND METHODS To characterize the pattern of inheritance and clinical features, 29 family members were evaluated by dermatologic, ophthalmologic, otorhinolaryn...

Dental fusion and agenesis present unique esthetic challenges for the dental team when discovered in a developing child. This article highlights treatment of a 9-year-old girl with fusion of a maxillary central and lateral incisor with a congenitally missing lateral over a 10-year period. The article defines the developmental anomalies, provides a review of treatment options for the clinical te...

Congenital absence of permanent second molar is an extremely rare condition, which may appear as part of a syndrome or as a non-syndromic form. Non-syndromic second molar agenesis combined with other types of teeth agenesis has occasionally been described in the literature but isolated cases are rarely observed. It might be caused by a number of complex interactions between genetic, epigenetic ...

The aim of the study was to test the hypothesis that the gene defect causing congenital absence of maxillary lateral incisors also causes narrowing of the dentition. A total of 81 patients with one or two congenitally missing lateral incisors were retrieved; 52 (64.2 per cent) patients presented bilateral agenesis, whereas 29 (35.8 per cent) had unilateral agenesis. The control group consisted ...

To report a rare case of a 19 year old female presenting with bilateral dacryocele and punctal and canalicular agenesis without epiphora. After clinical and radiological examination, the patient was found to have bilateral lacrimal gland agenesis as well. No other dental, otological or systemic abnormality suggestive of lacrimo-auricular-dento-digital syndrome was detected. She was managed with...

Tooth agenesis in Malay children, hitherto unreported, was assessed retrospectively from orthopantomograms of 834 healthy children aged 12-16 years who attended the Dental Clinic of Universiti Sains Malaysia. All teeth, including third molars, were assessed for agenesis. On an average, 2.3 teeth were missing per child. Missing third molars were found in 25.7% of children with one or two third m...

BACKGROUND Agenesis of mandibular incisors can lead to compromised dental and facial aesthetics and therefore requires appropriate treatment. When retained primary incisors are associated to this condition, a medium-term restoration may be provided before any definitive treatment to provide aesthetic relief to the young patient. CASE REPORT The aim of this paper is to discuss the aesthetic ma...

Neuroblastoma, a malignant tumor of the sympathetic nervous system and the most common extracranial solid tumor in childhood, arises from embryonic neural crest cells. Tooth development begins before birth and continues for 12–14 years with the development of the third molar for several years. Abnormal events that occur during odontogenesis give permanent damage. Whereas the impact of multimoda...