Osteons, the main organizational components of human compact bone, are cylindrical structures composed layers mineralized collagen fibrils, called lamellae. These lamellae have different orientations, degrees organization, and mineralization where intrafibrillar extrafibrillar minerals intergrown into one continuous network oriented crystals. While cellular activity is clearly source organic ma...

The aim of this investigation was to evaluate the osteoinductive property of autogenous demineralized dentin matrix (ADDM) on experimental surgical bone defects in the parietal bone of rabbits using the guided bone regeneration (GBR) technique incorporating human amniotic membrane (HAM). Thirty-six rabbits were divided into 2 groups, HAM and ADDM+HAM. It was possible to conclude that HAM did no...

STUDY DESIGN Review article, review of literature. OBJECTIVE To review the bone graft options that exist for posterolateral and posterior interbody lumbar fusion. SUMMARY OF BACKGROUND DATA As the number of lumbar fusion surgeries has increased over the last decade, alternative methods of grafting have been developed. Iliac crest autograft bone has traditionally been used for lumbar fusion....

Introduction RTI Biologics, Inc. (RTI) currently produces allograft demineralized bone matrix (DBM) paste products that are manufactured under strict aseptic conditions using single donors. All donors are subjected to rigorous screening, prior to processing, to ensure that no transmissible pathogens are present in donor material. In addition, a terminal sterilization procedure has been introduc...