Ixabepilone (Ixempra) is a member of a new class of cytotoxic agents, the epothilones. Epothilones promote tubulin polymerization in vitro and demonstrate antitumor activity. This article reviews the preclinical and clinical data that have led to the approval of ixabepilone for patients with locally advanced or metastatic breast cancer for whom anthracycline and taxane treatments have failed.

This Book Review is brought to you for free and open access by the Tampa Library at Scholar Commons. It has been accepted for inclusion in Genocide Studies and Prevention: An International Journal by an authorized administrator of Scholar Commons. For more information, please contact [email protected]. Recommended Citation Powell, Christopher Ph.D. (2015) "Book Review: Warning Signs of Gen...

background: cesarean delivery is a surgery for deliver a baby. women with previous cesarean delivery (cd) must often choose between a vaginal delivery (vd) and repeat cd. our aim of this study was to investigate factors associated with preference for cd in neyshabur pregnant women with previous cd. methods: a cross‑sectional study was conducted on all pregnant women (who had previous caesarean ...

background: nowadays, there has been a growing trend of caesarean sections in iran. one reason would be the mother’s desire. increased maternal self‑efficacy can be an important step to reduce percentage of cesarean. this study aimed to determine the effectiveness of training‑based strategies to increase the self‑efficacy for choosing delivery method among pregnant women in shahrekord city. met...

Students of social movements have long struggled with the question how relatively abstract political opportunities, such as elite divisions, affect unorganized activists without much knowledge of politics. We argue that the relationship between institutional opportunities and decisions to mobilize may take the form of trickle-down politics. In this view activists are affected by political oppor...

BACKGROUND Pulsed administration of nitric oxide has proven effective in relieving pulmonary hypertension and in improving oxygenation. With this delivery method the nitric oxide administration to low ventilated lung regions is avoided with subsequent enhancement in oxygenation. This study presents (i) pulsed administration technique for nitric oxide during artificial ventilation, (ii) evaluati...

This paper evaluates the use of STPA in a heatlhcare setting specifically a complex setting involving controllers participating in multiple processes at one time. This is a scenario that has not been explored with STPA before but is the status quo in most healthcare systems. In an intensive care unit, the process of providing care to patients is comprised of many processes including drug delive...

background: the increasing number of cesarean section is a great concern in many countries. in iran cesarean section rate has been steadily rising from 35% in 2000 to 40% in 2005. preferences for cesarean are often associated with some factors. objective: to investigate factors associated with preference for cesarean delivery, with special emphasis on pregnant women’s preferences in first pregn...