نتایج جستجو برای: deguelin
تعداد نتایج: 136 فیلتر نتایج به سال:
Journal:
:Chemistry - A European Journal
2010
2014
Chih-Shou Chen
Dong-Ru Ho
Fei-Yun Chen
Chang-Rong Chen
Yu-De Ke
Jyan-Gwo Joseph Su
At high cytotoxic concentrations, actinomycin D (ActD) blocks transcription, decreasing levels of MDM2 and thus causing p53 stabilization. At low cytostatic concentrations, ActD causes ribosomal stress, which decreases MDM2 activity, resulting in p53 stabilization and activation. ActD can thus be used for p53-based cyclotherapy. We analyzed pathways mediating ActD-induced p53 expression. Inhibi...
Journal:
:Oncotarget
2017
Deguelin as a Chemopreventive Agent in Mouse Lung Tumorigenesis Induced by Tobacco Smoke Carcinogens
Journal:
:JNCI: Journal of the National Cancer Institute
2005
Journal:
:International Journal of Cancer
2007
Journal:
:Journal of Cellular and Molecular Medicine
2008
Journal:
:Acta Pharmacologica Sinica
2005
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